高海拔暴露对人体骨的影响  

Effects of High Altitude Exposure on Human Bone

作　　者：朱俗莹 石志酉 陈艳丽 邬云红 ZHU Suying;SHI Zhiyou;CHEN Yanli;WU Yunhong(Medicine College of Xizang University,Lhasa 850000,Xizang,China;School of Medicine,Xizang Minzu University,Xianyang 712082,Shaanxi,China;Department of Endocrinology,Hospital of Chengdu Office of People's Governmentof Xizang Autonomous Region,Chengdu 610041,Sichuan,China)

机构地区：[1]西藏大学医学院,西藏拉萨850000 [2]西藏民族大学医学院,陕西咸阳712082 [3]西藏自治区人民政府驻成都办事处医院内分泌科,四川成都610041

出　　处：《医学信息》2025年第8期178-182,共5页Journal of Medical Information

基　　金：西藏自治区中央引导地方项目(编号:XZ202102YD0026C)。

摘　　要：中国的骨质疏松症患病率高,严重影响中老年人群的身体健康和生活质量,高原地区情况更加严峻。高原环境对骨密度和骨质疏松症的影响有待进一步研究和阐明。本研究总结高原环境对不同人群骨密度、骨代谢的影响,从HIF基因出发分析高原骨质疏松症的发生机制,并基于动物模型归纳了预防高原骨质疏松症的方案,旨在为高原地区骨质疏松症预防提供帮助。The prevalence of osteoporosis in China is high,which seriously affects the health and quality of life of middle-aged and elderly people,and the situation in the plateau area is more severe.The effects of plateau environment on bone mineral density and osteoporosis need to be further studied and elucidated.This study summarized the effects of plateau environment on bone mineral density and bone metabolism in different populations,analyzed the mechanism of plateau osteoporosis from HIF gene,and summarized the prevention of plateau osteoporosis based on animal models,aiming to provide help for the prevention of osteoporosis in plateau areas.

关 键 词：高原 骨质疏松症 骨代谢 

分 类 号：R580[医药卫生—内分泌]