基于血细胞参数形成的新型比值在慢性阻塞性肺疾病中的研究价值  

Research Value of Novel Ratios Based on Blood Cell Parameters in Chronic Obstructive Pulmonary Disease

作　　者：冯钰强 李文 FENG Yuqiang;LI Wen(The First Clinical Medical College of Guangdong Medical University,Zhanjiang 524000,Guangdong,China;Department of Respiratory and Critical Care Medicine,Affiliated Hospital of Guangdong Medical University,Zhanjiang 524000,Guangdong,China)

机构地区：[1]广东医科大学第一临床医学院,广东湛江524000 [2]广东医科大学附属医院呼吸与危重症医学科,广东湛江524000

出　　处：《医学信息》2025年第8期187-192,共6页Journal of Medical Information

摘　　要：慢性阻塞性肺疾病(COPD)是一种具有持续性呼吸道症状和不完全可逆性气流受限的疾病,广泛认可的COPD发病机制是免疫失衡和炎症假说,动态监测炎症指标及免疫功能的变化对指导临床治疗有着重要意义。多项研究证实,全血细胞计数参数衍生的简便新型生物标志物在评估COPD患者的疾病严重程度和预后方面发挥着不可替代的关键作用。本文通过回顾近年来有关血细胞计数比值在COPD发生和住院不良预后之间的相关研究进行综述,以期为COPD治疗和干预提供更具针对性的策略。Chronic obstructive pulmonary disease(COPD) is a disease characterized by persistent respiratory symptoms and partially reversible airflow limitation.The widely accepted mechanism of COPD is the imbalance of immunity and the hypothesis of inflammation.Dynamic monitoring of inflammation markers and changes in immune function plays an important role in guiding clinical treatment.Numerous studies have confirmed that novel biomarkers derived from blood cell count parameters play an irreplaceable key role in evaluating the severity and prognosis of COPD patients.This article reviews the recent studies on the relationship between the ratio of blood cell count and the occurrence of COPD and the poor prognosis of hospitalization,in order to provide more targeted strategies for the treatment and intervention of COPD.

关 键 词：慢性阻塞性肺疾病 血细胞参数 生物标志物 

分 类 号：R563[医药卫生—呼吸系统]