超早产儿临床特征及死亡的危险因素logistic分析  

Logistic Analysis of Clinical Characteristics and Risk Factors for Mortality in Preterm Infant

作　　者：李杰 Li Jie(The First Affiliated Hospital of Nanyang Wolong District,Nanyang,Henan,473006,China)

机构地区：[1]南阳市卧龙区第一人民医院,河南南阳473006

出　　处：《黑龙江医学》2025年第7期780-782,共3页Heilongjiang Medical Journal

摘　　要：目的:探讨超早产儿(EPI)临床特征及死亡的危险因素。方法:回顾性分析2022年1月—2023年6月南阳市卧龙区第一人民医院收治的112例EPI,根据EPI临床结局(存活、死亡)进行分组,比较两组的临床特征,经单因素分析与logistic回归分析以明确EPI死亡的危险因素。结果:112例EPI中,死亡35例(31.25%),死亡组胎龄<26周、出生体重<750 g、多胎、出生1周内肺出血、出生1周内坏死性小肠结肠炎(NEC)、出生1周内低体温、有创机械通气、母体身体质量指数(BMI)≥28 kg/m^(2)的EPI占比较存活组更高。logistic回归分析结果显示,多胎、出生1周内肺出血、出生1周内NEC、出生1周内低体温、有创机械通气、母体BMI≥28 kg/m^(2)是影响EPI死亡的独立危险因素(OR=5.527、5.962、5.033、2.109、3.620、2.963,P<0.05)。结论:EPI的死亡风险较高,多胎、出生1周内肺出血、出生1周内NEC、出生1周内低体温、有创机械通气、母体BMI均与其存在密切关系,需要重点关注。Objective:To explore the clinical characteristics and risk factors for mortality in ultra premature infants(EPI).Methods:A retrospective analysis was conducted on 112 cases of EPI who were admitted in the First People’s Hospital of Wolong District,Nanyang City from January 2022 to June 2023.Grouping based on EPI clinical outcomes survival,death,the clinical characteristics of the two groups were compared,and univariate and logistic multiple regression analysis were performed to identify the risk factors for EPI mortality.Results:Among the 112 cases of EPI,35 cases(31.25%)were died.In comparision of the survival group,the proportion of EPI with gestational age<26 weeks,birth weight<750 g,multiple pregnancies,pulmonary hemorrhage within 1 week of birth,necrotizing enterocolitis(NEC)within 1 week of birth,hypothermia within 1 week of birth,invasive mechanical ventilation,and maternal body mass index(BMI)≥28 kg/m^(2) of the death group was higher.The results of logistic multivariate analysis showed that multiple births,pulmonary hemorrhage within 1 week of birth,NEC within 1 week of birth,hypothermia within 1 week of birth,invasive mechanical ventilation,and maternal BMI≥28 kg/m^(2) were independent risk factors for EPI death(OR=5.527,5.962,5.033,2.109,3.620,2.963;P<0.05).Conclusion:EPI has higher risk of mortality,with multiple pregnancies,pulmonary hemorrhage within one week of birth,NEC within 1 week of birth,hypothermia within 1 week of birth,invasive mechanical ventilation,and maternal BMI are all closely related to them,which requires special attention.

关 键 词：超早产儿 临床特征 死亡 危险因素 

分 类 号：R722.6[医药卫生—儿科]