梧州地区沙眼衣原体、解脲脲原体的感染现状分析  

Analysis of Infection Status of Chlamydia Trachomatis and Ureaplasma Urealyticum in Wuzhou Area

作　　者：严坚恩 黄小娟 余永雄 Yan Jian’en;Huang Xiaojuan;Yu Yongxiong(Department of Laboratory,Wuzhou Maternal and Child Health Hospital,Wuzhou,Guangxi,543000,China)

机构地区：[1]梧州市妇幼保健院检验科,广西梧州543000

出　　处：《黑龙江医学》2025年第7期854-857,共4页Heilongjiang Medical Journal

摘　　要：目的:分析广西梧州地区沙眼衣原体(CT)、解脲脲原体(UU)感染情况及特征,为临床诊断与治疗提供实验室依据。方法:回顾性分析2019年1月—2023年12月于梧州市妇幼保健院就诊的15024例患者临床资料,样本采用荧光探针实时聚合酶链式反应(PCR)技术同时进行CT和UU检测,并结合其临床资料,对检测结果进行统计学分析,分析不同年份、不同性别、不同年龄段、不同临床诊断患者CT、UU及CT+UU混合感染检出情况。结果:15024例检测者中,CT、UU、CT+UU混合感染的总体检出率分别为1.36%、41.72%、4.31%。UU的检出率明显高于CT和CT+UU混合感染,差异均有统计学意义(χ^(2)=19.106、22.914、19.552,P<0.001)。近年来CT检出率呈下降趋势,UU检出率呈下降又上升的U型分布,CT+UU混合感染情况无明显变化规律。女性UU和CT+UU混合感染的检出率均明显高于男性,差异均有统计学意义(χ^(2)=288.542、17.038,P<0.001)。不同年龄段检测者中,男女感染均呈年轻化。临床诊断明确的检测者中,合计检出率排在前三位的为异位妊娠(60.81%)、月经不调(57.41%)、女性不孕症(54.23%)。结论:梧州地区CT、UU总感染率较高,UU有上升趋势,女性感染情况明显高于男性,CT、UU感染呈年轻化趋势,提示应注重健康宣教、加强个人防护、积极参与体检并及时治疗。Objective:To analyze the infection status and characteristics of chlamydia trachomatis(CT)and ureaplasma Urealyticum(UU)in Wuzhou,Guangxi,and provide laboratory basis for clinical diagnosis and treatment.Methods:A retrospective analysis was conducted on the samples of 15024 patients who were treated in Wuzhou Maternal and Child Health Hospital from January 2019 to December 2023.CT and UU detection were performed by real-time PCR with fluorescent probes,and the test results were statistically analyzed in combination with their clinical data.The detection of CT,UU and CT+UU in patients with different years,genders,ages and clinical diagnoses were analyzed.Results:The overall detection rates of CT,UU and CT+UU mixed infection were 1.36%,41.72%and 4.31%,respectively.The detection rate of UU was significantly higher than that of CT and CT+UU mixed infection,the difference was statistically significant(χ^(2)=19.106,22.914,19.552;P<0.001).In recent years,the detection rate of CT showed a decreasing trend.The detection rate of UU showed a U-shaped distribution of decreasing and increasing.There was no significant change in CT+UU mixed infection.The detection rates of UU and CT+UU mixed infection in females were significantly higher than those in males,and the difference was statistically significant(χ^(2)=0.581,288.542,17.038;P<0.001).Among different age groups,and both men and women were infected at a younger age.Among the patients with definite clinical diagnosis,the total detection rate of ectopic pregnancy was 60.81%,irregular menstruation was 57.41%,and female infertility was 54.23%.Conclusion:The total infection rate of Chlamydia trachomatis(CT)and Uaplasma Uyticum(UU)was higher in Wuzhou,and UU aplasma UU was on the rise.The infection rate of women was significantly higher than that of men.The infection rate of CT and UU was younger,suggesting that we should pay attention to health education,strengthen personal protection,and actively participate in physical examination and timely treatment.

关 键 词：梧州地区 沙眼衣原体 解脲脲原体 感染 

分 类 号：R374[医药卫生—病原生物学]