经皮二氧化碳分压/氧分压监测在无创辅助通气呼吸窘迫综合征患儿治疗中的应用  

Application of Transcutaneous Carbon Dioxide Partial Pressure/Oxygen Partial Pressure Monitoring in the Treatment of Pediatric Patients with Respiratory Distress Syndrome Undergoing Non-Invasive Assisted Ventilation

作　　者：黄洁兴 崔伟伦 刘素丽 蔡杰荣 何淑儿 HUANG Jiexing;CUI Weilun;LIU Suli;CAI Jierong;HE Shuer(Department of Pediatrics,The Affiliated Panyu Central Hospital of Guangzhou Medical University,Guangzhou,Guangdong 511400,China)

机构地区：[1]广州医科大学附属番禺中心医院儿科,广东广州511400

出　　处：《临床肺科杂志》2025年第5期687-691,共5页Journal of Clinical Pulmonary Medicine

摘　　要：目的分析经皮二氧化碳分压(TcPCO_(2))、经皮氧分压(TcPO_(2))监测在无创辅助通气RDS患儿治疗中的应用。方法选取2022年1月至2023年12月于我院住院的100例RDS早产儿纳入研究,均经无创通气治疗,根据血气监测方式将其分为观察组(n=48)和对照组(n=52),观察组患儿于治疗过程中予以监测TcPCO_(2)及TcPO_(2);对照组患儿于治疗过程中予以监测动脉二氧化碳分压(PaCO_(2))及动脉氧分压(PaO_(2)),于辅助通气30min、6h、12h及24h时比较两组血气分析指标,并分析各时间点TcPCO_(2)与PaCO_(2)、TcPO_(2)与PaO_(2)的相关性,记录两组临床疗效及并发症。结果两组辅助通气30min、6h、12h及24h时TcPCO_(2)与PaCO_(2)、TcPO_(2)与PaO_(2)比较差异无统计学意义(P>0.05);两组辅助通气30min、6h、12h及24h时TcPCO_(2)与PaCO_(2)分压呈下降趋势,而TcPO_(2)与PaO_(2)分压呈上升趋势,组内比较差异有统计学意义(P<0.05);经Pearson分析显示,辅助通气30min、6h、12h及24h时的TcPCO_(2)与PaCO_(2)均呈正相关(P<0.05);辅助通气30min、6h、12h及24h时的TcPO_(2)与PaO_(2)均呈正相关(P<0.05);两组临床治疗总有效率比较差异无统计学意义(P>0.05);两组患儿并发症主要表现为肺部感染、腹胀、肺气压伤、视网膜病变等,与对照组比较,观察组患儿总并发症发生率较低(P<0.05)。结论TcPCO_(2)与TcPO_(2)联合监测可准确评估RDS患儿血气状况,其在无创辅助通气RDS治疗中应用价值较高,且临床较为安全。Objective To Analyze the application of Transcutaneous Carbon Dioxide Partial Pressure(TcPCO_(2))and Transcutaneous partial pressure of oxygen(TcPO_(2))monitoring in the treatment of pediatric patients with respiratory distress syndrome(RDS)undergoing non-invasive assisted ventilation.Methods A total of 100 premature infants with RDS hospitalized in our hospital from January 2022 to December 2023 were included in the study.All of them were treated with non-invasive ventilation and divided into the observation group(n=48)and control group(n=52)according to blood gas monitoring methods.Children in the observation group were monitored with TcPCO_(2)and TcPO_(2)during treatment.In the control group,arterial partial pressure of carbon dioxide(PaCO_(2))and arterial partial pressure of oxygen(PaO_(2))were monitored during treatment.Blood gas analysis indexes of the two groups were compared at 30min,6h,12h,and 24h of assisted ventilation,and correlations between TcPCO_(2)and PaCO_(2),TcPO_(2)and PaO_(2)were analyzed at each time point.The clinical efficacy and complications of the two groups were recorded.Results There was no significant difference between TcPCO_(2)and PaCO_(2),TcPO_(2),and PaO_(2)during 30 minutes,6 hours,12 hours,and 24 hours of respiratory ventilation between the two groups(P>0.05).At 30 minutes,6 hours,12 hours,and 24 hours of respiratory ventilation,the partial pressures of TcPCO_(2)and PaCO_(2)showed a downward trend,while the partial pressures of TcPO_(2)and PaO_(2)showed an upward trend.There was a significant difference within the groups(P<0.05).Pearson analysis showed that there was a positive correlation between TcPCO_(2)and PaCO_(2)at 30min,6h,12h,and 24h(P<0.05).At 30 minutes,6 hours,12 hours,and 24 hours of assisted ventilation,TcPO_(2)was positively correlated with PaO_(2)(P<0.05).There was no difference in the total effective rate between the two clinical treatment groups(P>0.05).The main complications of the two groups of children were pulmonary infection,abdominal distension,pulmonary b

关 键 词：经皮二氧化碳分压 经皮氧分压 无创辅助通气 呼吸窘迫综合征 

分 类 号：R722.1[医药卫生—儿科]