CT定量分析竖脊肌横断面积对支气管扩张疾病的临床价值  

The clinical significance of CT quantitative analysis of the Cross-sectional Area of Erector Spinae muscle in bronchiectasis

作　　者：方莎 涂平华 王丹[1,2] 吴展陵[1] FANG Sha;TU Pinghua;WANG Dan;WU Zhanling(Respiratory medicine,Xiaogan Hospital Affiliated to Wuhan University of Science and Technology,Xiaogan,Hubei 432000,China;Medical College,Wuhan University of Science and Technology,Wuhan,Hubei 430081,China)

机构地区：[1]武汉科技大学附属孝感医院呼吸内科,湖北孝感432000 [2]武汉科技大学医学部医学院,湖北武汉430081

出　　处：《临床肺科杂志》2025年第5期712-716,共5页Journal of Clinical Pulmonary Medicine

基　　金：孝感市自然科学计划项目(XGKJ2022010004)。

摘　　要：目的分析竖脊肌横断面积(ESMcsa)与支气管扩张患者疾病严重程度及预后的相关性。方法回顾性分析2023年1月-2023年12月收治的160例明确诊断为支气管扩张的患者,根据1年内死亡率分为生存组与死亡组,比较两组患者的一般资料、FEV_(1)%pred、ESMcsa,分析影响支气管扩张患者1年内死亡的危险因素。结果多因素Logistics回归分析示高龄、低白蛋白、BSI评分、E-FACED评分、低FEV_(1)%pred、ESMcsa减少是住院支气管扩张恶化患者1年内死亡的独立危险因素,Spearman相关性分析结果显示,支气管扩张患者ESMcsa与BMI、Alb、FEV_(1)%pred呈正相关,与年龄、BSI评分、E-FACED评分呈负相关。Kaplan-Meier生存曲线显示ESMcsa越小,总体生存率越小,差异有统计学意义(P<0.01)。结论ESMcsa是支气管扩张恶化住院患者1年死亡率的保护因素,ESMcsa越低的患者疾病严重程度更高。ESMcsa可作为支扩患者严重程度及恶化的预测因素。Objective To investigate the association between erector spinal muscle cross-sectional area(ESMcsa)and disease severity as well as prognosis in patients with bronchiectasis.Methods A retrospective analysis was performed on 160 patients with definite diagnosis of bronchiectasis admitted from January 2023 to December 2023,and they were retrospectively divided into survival group and death group according to 1-year mortality.General data,FEV_(1)%pred and ESMcsa of the two groups were compared to analyze the risk factors affecting the death of patients with bronchiectasis within 1 year.Results Multi-factor Logistics regression analysis showed that advanced age,low albumin,BSI score,E-FACED score,low FEV_(1)%pred and reduced ESMcsa were independent risk factors for death within 1 year in hospitalized patients with worsening bronchiectasis.Spearman correlation analysis showed that,In patients with bronchiectasis,ESMcsa was positively correlated with BMI,Alb,and FEV_(1)%pred,and negatively correlated with age,BSI score,and E-FACED score.Kaplan-Meier survival curve showed that the smaller ESMcsa was,the smaller the overall survival rate was,and the difference was statistically significant(P<0.01).Conclusion ESMcsa is a protective factor for 1-year mortality in hospitalized patients with worsening bronchiectasis,and patients with lower ESMcsa have higher disease severity.ESMcsa can be used as a predictor of severity and progression in patients with bronchiectasis.

关 键 词：支气管扩张 竖脊肌横断面积 CT定量分析 

分 类 号：R562[医药卫生—呼吸系统]