左心疾病相关性肺动脉高压的治疗进展  

Advances in the treatment of pulmonary hypertension due to left heart disease

作　　者：汪程 张航 WANG Cheng;ZHANG Hang(Department of Cardiology,Nanjing First Hospital,Nanjing Medical University,Nanjing,210001,China)

机构地区：[1]南京市第一医院,南京医科大学附属南京医院心内科,南京210001

出　　处：《临床心血管病杂志》2025年第3期181-187,共7页Journal of Clinical Cardiology

摘　　要：肺动脉高压(肺高压)是一大类以肺循环血压持续升高为特征且致残率、致死率极高的进展性疾病。其中,左心疾病相关性肺高压是最常见的原因,其病情更重、预后更差、病死率更高。目前该类肺高压缺乏有效的治疗药物,并且国内外相关研究十分有限。本文将概述左心疾病相关性肺高压的定义、分类及病理生理学机制,重点阐述并归纳其临床分型及其相关治疗的研究进展。Pulmonary hypertension is a group of progressive diseases characterized by sustained elevation of pulmonary circulation blood pressure,with a high rate of disability and mortality.Among them,pulmonary hypertension due to left heart disease(PH-LHD)is the most common cause,characterized by more severe conditions,poorer prognosis,and higher mortality rates.Currently,there is a lack of effective treatment drugs for this type of pulmonary hypertension,and related research both domestically and internationally is very limited.This review will summarize the definition,classification,and pathophysiology of PH-LHD,focusing on elaborating and summarizing the clinical typing and research progress in its related treatments.

关 键 词：肺动脉高压 左心疾病 治疗 药物 

分 类 号：R544.1[医药卫生—心血管疾病]