肺部高频超声对新生儿呼吸窘迫综合征严重程度及预后的评估价值  

Evaluation value of high-frequency lung ultrasound in assessing the severity and prognosis of neonatal respiratory distress syndrome

作　　者：刘惠丽 王莉 吴豪杰 张艺森 LIU Hui-li;WANG Li;WU Hao-jie;ZHANG Yi-sen(Department of Ultrasound,Department of Neonatology,Zhumadian 463000,Henan,CHINA;Department of Ultrasound,Zhumadian Central Hospital,Zhumadian 463000,Henan,CHINA)

机构地区：[1]驻马店市中心医院超声科,河南驻马店463000 [2]驻马店市中心医院新生儿科,河南驻马店463000

出　　处：《海南医学》2025年第8期1154-1157,共4页Hainan Medical Journal

基　　金：2021年度河南省医学科技攻关计划联合共建项目和软科学项目(编号:LHGJ20210619)。

摘　　要：目的探讨肺部高频超声评分对新生儿呼吸窘迫综合征(NRDS)严重程度及预后的评估价值。方法前瞻性选择2022年4月至2024年4月驻马店市中心医院收治的100例NRDS患儿作为研究组,根据病情严重程度将患儿分为轻度组(n=22)、中度组(n=53)和重度组(n=25),并根据预后将患儿分为预后良好组(n=90)和预后不良组(n=10),另选择90例无肺部疾病的新生儿作为对照组。比较所有受检者的肺部高频超声评分,采用受试者工作特征(ROC)曲线分析肺部高频超声评分对NRDS预后的评估价值。结果研究组患儿的肺部高频超声评分为(19.91±3.20)分,明显高于对照组的(2.02±0.31)分,差异有统计学意义(P<0.05);重度组患儿的肺部高频超声评分为(25.16±4.04)分,明显高于中度组的(19.94±3.11)分和轻度组的(14.06±2.01)分,且中度组患儿的肺部高频超声评分明显高于轻度组,差异均有统计学意义(P<0.05);预后不良组患儿的肺部高频超声评分为(23.35±2.40)分,明显高于预后良好组的(18.81±1.94)分,差异有统计学意义(P<0.05)。ROC曲线分析结果显示,肺部高频超声评分对NRDS预后的AUC为0.955,敏感度为90.00%,特异度为93.00%(P<0.05)。结论NRDS患儿的肺部高频超声评分显著升高,与病情严重程度及预后密切相关,可有效评估预后。Objective To explore the value of high-frequency lung ultrasound(LUS)scoring in assessing the severity and prognosis of neonatal respiratory distress syndrome(NRDS).Methods A prospective study was conduct-ed on 100 NRDS infants admitted to Zhumadian Central Hospital from April 2022 to April 2024 as the study group.Based on disease severity,the infants were divided into mild(n=22),moderate(n=53),and severe(n=25)groups,and fur-ther classified into favorable prognosis(n=90)and poor prognosis(n=10)groups.Additionally,90 healthy newborns with-out pulmonary diseases were selected as the control group.High-frequency LUS scores were compared among all partici-pants.Receiver operating characteristic(ROC)curve analysis was used to evaluate the prognostic value of LUS scores.Results The LUS score was in the study group was significantly higher than in the control group:(19.91±3.20)points vs(2.02±0.31)points,P<0.05.The severe group had a significantly higher LUS score than the moderate and mild groups:(25.16±4.04)points vs(19.94±3.11)points vs(14.06±2.01)points,and the moderate group scored higher than the mild group(all P<0.05).The poor prognosis group showed a significantly higher LUS score than the favorable prognosis group:(23.35±2.40)points vs(18.81±1.94)points,P<0.05.ROC analysis revealed that the LUS score had an AUC of 0.955 for pre-dicting NRDS prognosis,with a sensitivity of 90.00%and specificity of 93.00%(P<0.05).Conclusion The high-frequen-cy LUS score is significantly elevated in NRDS infants and closely correlates with disease severity and prognosis,serving as an effective tool for prognostic assessment.

关 键 词：新生儿 呼吸窘迫综合征 肺部超声 预后 

分 类 号：R722.1[医药卫生—儿科]