针灸疗法治疗冠心病的机制与临床研究进展  

Mechanism and clinical research progress of acupuncture therapy in the treatment of coronary heart disease

作　　者：詹梓廉 王靖阳 冯禾 刘玄 徐强[2] ZHAN Zilian;WANG Jingyang;FENG He;LIU Xuan;XU Qiang(Postgraduate School,Tianjin University of Traditional Chinese Medicine,Tianjin 301617,China;Department of Cardiovascular Medicine,The Second Affiliated Hospital of Tianjin University of Traditional Chinese Medicine,Tianjin 300250,China)

机构地区：[1]天津中医药大学研究生院,天津301617 [2]天津中医药大学第二附属医院心血管内科,天津300250

出　　处：《天津中医药》2025年第4期526-531,共6页Tianjin Journal of Traditional Chinese Medicine

基　　金：国家自然科学基金面上项目(82374195)。

摘　　要：综述近5年来针灸治疗冠心病的国内外临床研究及机制研究进展。研究结果显示,针灸作为一种非药物治疗方法,在缓解心绞痛、改善心肌缺血状态、增强心肺功能、提升运动耐力和患者生存质量方面展现出积极效果,且不良反应较少。针灸治疗冠心病的作用机制复杂,涉及多层次、多通路和多靶点的综合效应,具体包括减轻心肌细胞损伤、调节自主神经系统平衡、抑制炎性反应等多个方面。尽管针灸治疗冠心病在临床和基础研究领域已取得一定进展,但仍需深入探索其作用机制,以期为未来针灸疗法的创新与发展提供新的科学依据,从而更好地服务于临床实践及科学研究。This article reviews the clinical research and mechanism research progress of acupuncture in the treatment of coronary heart disease(CHD)both domestically and internationally in the past five years.The research findings indicated that acupuncture,as a non-pharmacological therapy,had demonstrated positive effects in alleviating angina pectoris,improving myocardial ischemia,enhancing cardiopulmonary function,increasing exercise tolerance,and improving patients’quality of life,with minimal adverse reactions.The mechanism of acupuncture in treating CHD was complex,involving comprehensive effects in multiple levels,multiple pathways,and multiple targets,specifically including reducing myocardial cell damage,regulating the balance of the autonomic nervous system,and inhibiting inflammatory responses and other aspects.Although some progress had been made in the clinical and basic research of acupuncture in the treatment of CHD,further exploration of its mechanism is still needed to carry out so as to provide new scientific evidence for the innovation and development of acupuncture therapy in the future,thereby better serving clinical practice and scientific research.

关 键 词：针灸 冠心病 临床评价 机制研究 综述 

分 类 号：R541.4[医药卫生—心血管疾病]