hs-cTnT、甲状腺功能与急性冠脉综合征患者PCI术后近期预后的关系  

The relationship between hs-cTnT,thyroid function,and short-term prognosis in patients with acute coronary syndrome after PCI

作　　者：王岚 郭锋[1] 漆峻岑 雷航 刘小群 WANG Lan;GUO Feng;QI Juncen;LEI Hang;LIU Xiaoqun(Department of Cardiovascular Medicine,Peng'an County People's Hospital,Nanchong 637800,Sichuan,China;Health Management Center,Deyang People's Hospital,Deyang 618099,Sichuan,China)

机构地区：[1]蓬安县人民医院心血管内科,四川南充637800 [2]德阳市人民医院健康管理中心,四川德阳618099

出　　处：《中南医学科学杂志》2025年第2期292-295,共4页Medical Science Journal of Central South China

基　　金：四川省医疗卫生与健康促进会省级科研项目(KY2022SJ0100)。

摘　　要：目的 探讨超敏肌钙蛋白T(hs-cTnT)、甲状腺功能与急性冠脉综合征(ACS)患者经皮冠脉介入术(PCI)后近期预后的关系。方法 选择ACS患者154例作为观察组,同时选取因胸痛或胸闷入院、冠状动脉造影未见狭窄患者100例作为对照组。比较两组hs-cTnT、甲状腺功能指标差异,同时分析观察组不同年龄、性别、疾病类型、预后的ACS患者hs-cTnT、甲状腺功能指标水平以及预后的影响因素。结果 观察组hs-cTnT高于对照组(P<0.05),游离三碘甲状腺原氨酸(FT3)和三碘甲状腺原氨酸(T3)低于对照组(P<0.05)。观察组急性心肌梗死(AMI)患者hs-cTnT高于不稳定型心绞痛(UAP)患者(P<0.05),而FT3和T3低于UAP患者(P<0.05)。观察组预后不良患者年龄、Gensini评分、hs-cTnT水平高于预后良好患者(P<0.05),FT3低于预后良好患者(P<0.05)。Logistic回归分析显示,年龄、Gensini评分、hs-cTnT和FT3是患者预后不良的影响因素(P<0.05)。结论 hs-cTnT和甲状腺功能指标FT3是ACS经皮冠脉介入术近期预后的影响因素,值得临床关注。Aim To investigate the relationship between high sensitivity cardiac troponin T(hs-cTnT),thyroid function and short-term prognosis of percutaneous coronary intervention(PCI) in patients with acute coronary syndrome(ACS).Methods A total of 154 ACS patients from our hospital were selected as the observation group,while 100 patients admitted due to chest pain or tightness but no stenosis observed on coronary angiography were selected as the control group.The differences in hs-cTnT and thyroid function indicators were compared between groups,and the differences among ACS patients with different ages,genders and prognoses were analyzed.Results The observation group had higher hs-cTnT(P<0.05) and lower free triiodothyronine(FT3) and triiodothyronine(T3) levels(P<0.05) compared with the control group.In the observation group,acute myocardial infarction(AMI) patients showed higher hs-cTnT(P<0.05) and lower FT3 and T3 levels(P<0.05) than unstable angina pectoris(UAP) patients.Patients in poor prognosis had higher age and Gensini scores(P<0.05),elevated hs-cTnT(P<0.05),and lower FT3(P<0.05) than those with good prognosis.Logistic regression analysis showed that age,Gensini score,hs-cTnT and FT3 were influencing factors for poor prognosis(P<0.05).Conclusion hs-cTnT and thyroid function indicator FT3 are influencing factors for short-term prognosis of PCI in ACS patients,which deserve clinical attention.

关 键 词：超敏肌钙蛋白T 甲状腺功能 急性冠脉综合征 经皮冠脉介入术 预后 

分 类 号：R543.3[医药卫生—心血管疾病]