环境及人体微生态与哮喘关系的研究进展  

Relationships of environment and human microbiota with asthma

作　　者：赵一凡 刘珈彤 李轶 王子朔 赵丽敏 ZHAO Yifan;LIU Jiatong;LI Yi;WANG Zishuo;ZHAO Limin(Department of Respiratory and Critical Care Medicine,Henan University People's Hospital,Henan Provincial People's Hospital,Zhengzhou,Henan 450003,China;Department of Respiratory and Critical Care Medicine,Zhengzhou University People's Hospital,Henan Provincial People's Hospital,Zhengzhou,Henan 450003,China;Department of Respiratory and Critical Care Medicine,Henan Provincial People's Hospital,Zhengzhou University People's Hospital,Henan University People's Hospital,Zhengzhou,Henan 450003,China)

机构地区：[1]河南大学人民医院、河南省人民医院呼吸与危重症医学科,河南郑州450003 [2]郑州大学人民医院、河南省人民医院呼吸与危重症医学科,河南郑州450003 [3]河南省人民医院呼吸与危重症医学科、郑州大学人民医院、河南大学人民医院,河南郑州450003

出　　处：《中华实用诊断与治疗杂志》2025年第3期215-220,共6页Journal of Chinese Practical Diagnosis and Therapy

基　　金：河南省医学科技攻关计划省部共建项目(SBGJ202302003)。

摘　　要：哮喘发病率逐年升高,已成为严重的全球性健康问题。环境及人体微生态与哮喘的发生发展密切相关,但相关性存在不同结论,作用机制仍需进一步探索。不同环境下微生物的差异可对哮喘产生不同影响。机体呼吸道及肠道的微生态变化与哮喘发病风险及哮喘严重程度关系密切。本文就外界环境、呼吸道及肠道微生态与哮喘关系的研究进展作一综述。With an annual rising prevalence,asthma has become a serious global health issue.The environmental and human microbiota are closely involved in the occurrence and development of asthma,but there are different conclusions regarding the correlation,and the mechanisms still require further research.Microbial differences in different environments may have different impacts on asthma.The changes of respiratory and intestinal microbiota are closely corelated with the risk and severity of asthma.This paper reviews the research progress of the relationships of environmental microbiota,respiratory microbiota and intestinal microbiota with asthma.

关 键 词：哮喘 环境微生态 呼吸道微生态 肠道微生态 

分 类 号：R56[医药卫生—呼吸系统]