基于MRI对单眼发病眼内期视网膜母细胞瘤患儿预后因素分析  

Analysis of prognostic factors in children of intraocular retinoblastoma with monocular disease-based on MRI

作　　者：李林[1] 徐重阳[2] 董春华[1] LI Lin;XU Chongyang;DONG Chunhua(Department of Medical Imaging,Children’s Hospital Affiliated to Shandong University,Ji’nan 250022,China;Physical Examination Center,Huaiyin People’s Hospital of Ji’nan City,Ji’nan 250022,China)

机构地区：[1]山东大学附属儿童医院医学影像科,山东济南250022 [2]济南市槐荫人民医院查体中心,山东济南250022

出　　处：《实用放射学杂志》2025年第3期467-470,共4页Journal of Practical Radiology

摘　　要：目的 探讨影响儿童视网膜母细胞瘤(RB)经选择性眼动脉化疗(SOAI)预后的相关因素.方法 回顾性分析256例单眼发病眼内期RB患儿 MRI及临床资料.分析诸因素对患儿预后的影响.结果 拥有较高信号强度增强率(△SI)、与视盘较远的距离、较小的肿瘤径线、不伴种植灶或较小的种植范围、内生型生长方式、较小的视网膜剥离范围、不伴临床高危因素、玻璃体无出血及眼球无缩小患儿的预后更佳(P<0.05),肿瘤与视盘距离、临床高危因素及肿瘤生长方式是影响预后的独立因子.结论 肿瘤与视盘距离、临床高危因素及肿瘤生长方式与预后密切相关,其他诸因素是评估患儿预后的重要指标.Objective To explore the relevant prognostic factors of retinoblastoma(RB)in children after selective ophthalmic artery infusion(SOAI).Methods The MRI and clinical data of 256 children with intraocular RB in monocular disease were analyzed retrospectively.The influence of various factors on the prognosis was analyzed.Results Chidren with higher signal intensity(△SI),longer distance from optic disc,smaller tumor diameter,no implant focus or small implant area,endogenous growth pattern,smaller retinal exfoliation area,no clinical risk factors,no vitreous hemorrhage,no eyeball shrinkage had better prognoses(P<0.05),the distance between tumor and optic disc,clinical risk factors and tumor growth pattern were independent prognostic factors.Conclusion The distance between tumor and optic disc,clinical risk factors and tumor growth pattern are closely related to the prognosis of children.Other factors can be used as important indicators to evaluate the prognosis of children.

关 键 词：磁共振成像 眼内期 单眼 视网膜母细胞瘤 预后 

分 类 号：R445.2[医药卫生—影像医学与核医学] R739.7[医药卫生—诊断学] R730.7[医药卫生—临床医学]