中药寿胎丸加减联合黄体酮治疗对先兆流产患者的影响  

Effect of Modified Shoutai Pill(寿胎丸加减)Combined with Progesterone on Patients with Threatened Miscarriage

作　　者：姚雪 屈明霞 易磊 YAO Xue;QU Mingxia;YI Lei(Traditional Chinese Medicine Hospital of Xinyang,Xinyang 464000,Henan,China)

机构地区：[1]信阳市中医院,河南信阳464000

出　　处：《实用中医内科杂志》2025年第4期135-138,共4页Journal of Practical Traditional Chinese Internal Medicine

基　　金：河南省信阳市软科学研究计划项目(2022-30)。

摘　　要：目的探讨寿胎丸加减联合黄体酮治疗先兆流产的临床疗效及作用机制。方法选取医院2021年1月—2024年1月收治的先兆流产患者80例,采用随机数字表法分为对照组(黄体酮治疗)和观察组(联合中药寿胎丸治疗)各40例,比较两组临床疗效及实验室指标。结果比较两组中医证候积分显示,治疗前两组指标差异均无统计学意义(P>0.05),治疗后观察组评分维度(流血时间、流血色质、腰膝酸软、阴道流血量和下腹疼痛坠胀积分)均低于对照组,差异均有统计学意义(P<0.05);比较两组血清性激素水平显示,治疗前两组指标差异均无统计学意义(P>0.05),治疗后观察组指标均优于对照组,差异均有统计学意义(P<0.05);比较两组超声指标显示,治疗前各指标差异均无统计学意义(P>0.05)。治疗后观察组患者各指标均显著较对照组更优,差异均有统计学意义(P<0.05);比较两组临床疗效显示,观察组治疗总有效率显著高于对照组,差异存在统计学意义(P<0.05)。结论在临床实践中,对于先兆流产患者,采用寿胎丸加减联合黄体酮治疗法具有显著疗效。经治疗后,患者临床症状得到明显改善,血清性激素水平有所提升,同时宫腔积血也得到了有效调整,显示出较高的临床应用价值。Objective To analyze the effect of Modified Shoutai Pill(寿胎丸加减)combined with progesterone treatment on patients with threatened miscarriage.Methods Eighty patients with threatened miscarriage admitted to the hospital from January 2021 to January 2024 were randomly divided into a control group(treated with progesterone)and an observation group(treated with Shoutai Pill),with 40 patients in each group.The clinical effects of the two groups were compared.Result:Comparing the scores of traditional Chinese medicine symptoms between the two groups,there was no statistically significant difference in the indicators before treatment(P>0.05).After treatment,the observation group had lower scores in terms of bleeding time,bleeding color,lumbar and knee soreness,vaginal bleeding volume and lower abdominal pain and swelling scores than the control group,and the differences were statistically significant(P<0.05).Comparing the serum hormone levels of the two groups,there was no statistically significant difference in the indicators between the two groups before treatment(P>0.05).After treatment,the indicators in the observation group were better than those in the control group,and the differences were statistically significant(P<0.05).Comparing the ultrasound indicators of the two groups,there was no statistically significant difference in each indicator before treatment(P>0.05).After treatment,all indicators in the observation group were significantly better than those in the control group,and the differences were statistically significant(P<0.05).Comparing the clinical efficacy of the two groups,the total effective rate of the observation group was significantly higher than that of the control group,and the difference was statistically significant(P<0.05).Conclusion In clinical practice,the combination of Modified Shoutai Pill and progesterone has significant therapeutic effects on patients with threatened miscarriage.After treatment,the patients'clinical symptoms were significantly improved,the serum hormone level

关 键 词：先兆流产 中药 寿胎丸 黄体酮 临床治疗 中医证候积分 血清性激素 疗效 

分 类 号：R714.21[医药卫生—妇产科学]