多发性骨髓瘤骨病胸腰椎压缩性骨折的诊治进展  

Progress in Diagnosis and Treatment of Thoracolumbar Vertebral Compression Fractures in Multiple Myeloma Bone Disease

作　　者：温少瑾[1] 孙凤歧[2] 申小惠[1] 展锐[1] 豆传辉 张文君[1] 王立 WEN Shaojin;SUN Fengqi;SHEN Xiaohui;ZHAN Rui;DOU Chuanhui;ZHANG Wenjun;WANG Li(Department of Hematology,Gansu Provincial Hospital of Traditional Chinese Medicine,Lanzhou 730050,Gansu,China;Department of Minimally Invasive Spine Orthopedics,Gansu Provincial Hospital of Traditional Chinese Medicine,Lanzhou 730050,Gansu,China)

机构地区：[1]甘肃省中医院血液科,甘肃兰州730050 [2]甘肃省中医院脊柱微创骨科,甘肃兰州730050

出　　处：《医学信息》2025年第7期177-181,共5页Journal of Medical Information

基　　金：甘肃省自然科学基金(编号:22JR5RA623)。

摘　　要：多发性骨髓瘤(MM)是一种恶性癌症,它通过B淋巴细胞增殖。多发性骨髓瘤骨病(MMBD)则会导致患者出现严重的症状,需要及时诊断和治疗。MMBD发病原因多种多样,其中一个重要因素就在于骨髓瘤患者骨质疏松,导致骨骼组织发生变化。MMBD中的脊柱骨折,尤其是胸腰椎多发性压缩骨折在临床比较常见,更容易被发现,因此,及时准确地对MMBD中的胸腰椎压缩骨折进行准确诊断,对于预防多发性骨髓瘤骨病的发生,提高患者生存质量,实施积极有效的治疗,具有重大意义。本文从MMBD的常见胸腰椎压缩性骨折的流行病学及诊断治疗方面做一综述,以期临床中减少误诊和漏诊,对早期明确诊断提供帮助。Multiple myeloma(MM) is a malignant cancer that proliferates through B lymphocytes.Multiple myeloma bone disease(MMBD) can lead to severe symptoms in patients and requires timely diagnosis and treatment.The causes of MMBD are various,and one of the important factors is osteoporosis in patients with myeloma,which leads to changes in bone tissue.Spinal fractures in MMBD,especially thoracolumbar multiple compression fractures,are more common in clinical practice and are more likely to be found.Therefore,timely and accurate diagnosis of thoracolumbar compression fractures in MMBD is of great significance for preventing the occurrence of multiple myeloma bone disease,improving the quality of life of patients,and implementing active and effective treatment.This article reviews the epidemiology,diagnosis and treatment of common thoracolumbar vertebral compression fractures in MMBD,in order to reduce misdiagnosis and missed diagnosis in clinical practice and provide help for early diagnosis.

关 键 词：胸腰椎压缩性骨折 多发性骨髓瘤 骨髓瘤骨病 

分 类 号：R246.6[医药卫生—针灸推拿学]