中医药改善艾滋病患者免疫功能的探索与进展  

Exploration and progress of improving immune function of AIDS patients with traditional Chinese medicine

作　　者：海如尼萨·艾则孜 马秀兰 Hairunisa·AIZEZI;MA Xiu-lan

机构地区：[1]新疆医科大学第四临床医学院,新疆乌鲁木齐830000 [2]新疆医科大学第四临床医学院艾滋病研究室,新疆乌鲁木齐830000

出　　处：《中国疗养医学》2025年第4期58-62,共5页Chinese Journal of Convalescent Medicine

基　　金：国家级自然科学项目基金(82260910)。

摘　　要：免疫功能缺陷是艾滋病患者最主要的临床表现,以持续损伤体内免疫细胞,导致免疫失衡、免疫细胞耗竭为主要特点,从而引发多种严重的并发症最终导致死亡。中医以辨证论治为指导思想,治疗艾滋病方面以扶正、祛邪为主要治疗方法,在临床实践中得到了良好的成效。前期多项研究显示,中医药以益气扶正固本的治疗方法治疗艾滋病后,患者的免疫功能得到改善,其中CD_(4)^(+)T细胞的数量提升最为显著,细胞、NK细胞、B细胞的功能有一定程度的改善,调节了免疫因子之间的平衡,从而提高患者生存质量,延长寿命,但仍缺乏深入的基础研究支持。故本文在查阅文献的基础上总结了近些年来中医对艾滋病病因病机的认识,并对中医药改善患者免疫功能方面的治疗研究进行了讨论,旨在为后期治疗艾滋病提供参考。Immune deficiency is the most important clinical manifestation of AIDS patients,which is characterized by sustained damage to immune cells in the body,resulting in immune imbalance and immune cell exhaustion,leading to a variety of serious complications and eventually death.TCM takes syndrome differentiation and treatment as the guiding ideology,and AIDS treatment takes supporting righteousness and dispelling evil in the body as the main treatment methods,which has obtained good results in clinical practice.A number of previous studies have shown that after the TCM supplementing Qi and enforcing strength treatment of AIDS,the immune function of patients has been improved,among which the number of CD4+T cells has increased most significantly,and the functions of T cells,NK cells and B cells have improved to a certain extent,regulating the balance between immune factors,thereby improving the quality of life of patients and prolonging their life span.However,there is still a lack of in-depth basic research support.Therefore,on the basis of literature review,this paper summarizes the understanding of the etiology and pathogenesis of AIDS in Chinese medicine in recent years,and discusses the therapeutic research on improving the immune function of patients with Chinese medicine,aiming to provide reference for the later treatment of AIDS.

关 键 词：中医理论 艾滋病 中药治疗 免疫调节 综述 

分 类 号：R259[医药卫生—中西医结合]