梅毒螺旋体的免疫逃逸机制与相关免疫学指标临床应用的研究进展  

Research Progress in Immune Escape Mechanism of Treponema Pallidum and Clinical Application of Related Immunological Indicators

作　　者：杨玉婷[1,2] 胥萍[1,2] YANG Yu-ting;XU Ping(Laboratory Center,Affiliated Infectious Disease Hospital of Soochow University,Suzhou Jiangsu 215131,China;Suzhou Medical College of Soochow University,Suzhou Jiangsu 215131,China)

机构地区：[1]苏州大学附属传染病医院检验中心,江苏苏州215131 [2]苏州大学苏州医学院,江苏苏州215131

出　　处：《抗感染药学》2025年第1期1-5,共5页Anti-infection Pharmacy

基　　金：苏州市科技局项目(SZS2020311,SLT2021012,SLI2021017)。

摘　　要：梅毒是由梅毒螺旋体感染引起的一种慢性、系统性的传染性疾病。在梅毒螺旋体感染发展为梅毒的过程中,梅毒螺旋体需要逃过机体的层层免疫应答,而对相关免疫学指标开展检测,可以帮助临床进行正确诊断,从而进行针对性治疗。该文从梅毒螺旋体的免疫逃逸机制和相关免疫学指标的临床应用等方面进行综述,旨在为梅毒的疾病诊断提供思路和帮助。Syphilis is a chronic and systemic infectious disease caused by the infection of Treponema pallidum.During the process of Treponema pallidum infection developing into syphilis,Treponema pallidum needs to evade the body's immune responses at various levels.Detecting related immunological indicators can assist clinicians in making accurate diagnoses,thus enabling targeted treatment.In this article,the immune escape mechanism of Treponema pallidum and the clinical application of related immunological indicators are reviewed to provide ideas and assistance for diagnosis of syphilis.

关 键 词：梅毒 梅毒螺旋体 免疫逃逸机制 免疫学指标 诊断 

分 类 号：R759.1[医药卫生—皮肤病学与性病学]