Fe_(3)O_(4)-Au-Ag复合纳米材料的合成及其作为拉曼光谱基底的应用  

Synthesis of Fe_(3)O_(4)-Au-Ag Composite Nanomaterials and Their Application as Raman Spectrum Substrate

作　　者：吴睿 周正 WU Rui;ZHOU Zheng(School of Chemistry and Environmental Science,Shaanxi University of Technology,Hanzhong 723000,China)

机构地区：[1]陕西理工大学化学与环境科学学院,陕西汉中723001

出　　处：《稀有金属与硬质合金》2025年第2期100-108,共9页Rare Metals and Cemented Carbides

基　　金：陕西省重点研发计划项目(2024GX-YBXM-318);陕西理工大学教育科研项目(SLGYKS2401,202410720020,JYYJ2023-16)。

摘　　要：以三乙醇胺水热法制备Fe_(3)O_(4)纳米粒子,柠檬酸钠共还原法合成纳米Au-Ag合金溶胶,并对Fe_(3)O_(4)纳米粒子进行表面氨基化修饰。随后将Au-Ag纳米粒子负载在Fe_(3)O_(4)上合成Fe_(3)O_(4)-Au-Ag磁性复合纳米材料,并借助XRD、UV-Vis、TEM和EDS等方法对复合材料进行表征。将该复合材料作为表面增强拉曼散射(SERS)基底,并利用标准工作曲线开辟了一种检测左氧氟沙星的新方法,同时做了加标回收实验,分析了Fe_(3)O_(4)-Au-Ag增强左氧氟沙星拉曼光谱的机理。SERS峰强度与左氧氟沙星浓度(10^(-7)~10^(-3)mol/L)对数之间呈相对较好的线性关系,标准工作曲线方程为y=957x+7516.2,相关系数R^(2)=0.9522。该方法具有良好的稳定性,相对标准偏差为2.2%;灵敏度较高,检出限为2×10^(-9)mol/L,加标回收率在93%以上。Fe_(3)O_(4)-Au-Ag增强左氧氟沙星拉曼光谱的机理包括电磁增强机理和化学增强机理以及三个增强模型(镜像模型、天线模型和避雷针模型)。此新方法有望用在农业、工业、环境、食品、医药和卫生等领域,实现对实际样品中抗生素的高灵敏检测。Fe_(3)O_(4) nanoparticles were prepared by triethanolamine hydrothermal method,nano Au-Ag alloy sol was synthesized by sodium citrate co-reduction method,and Fe_(3)O_(4) nanoparticles were modified by surface amination.Subsequently,Au-Ag nanoparticles were loaded onto Fe_(3)O_(4) to synthesize Fe_(3)O_(4)-Au-Ag magnetic composite nanomaterials,and the composite materials were characterized using XRD,UV-Vis,TEM,and EDS.The composite materials were used as a surface-enhanced Raman scattering(SERS)substrate and a new method for detecting levofloxacin was developed using a standard working curve.Spiked recovery experiments were also conducted.In addition,the mechanism of Fe_(3)O_(4)-Au-Ag enhancing Raman spectrum of levofloxacin was analyzed.There is a relatively good linear relationship between the SERS peak intensity and the logarithm of levofloxacin concentration(10^(-7)~10^(-3)mol/L).The standard working curve equation is y=957x+7516.2,and the correlation coefficient R^(2) is 0.9522.This method has good stability with a relative standard deviation of 2.2%,and its sensitivity is relatively high with a detection limit of 2×10^(-9)mol/L and spiked recovery rate of over 93%.The mechanism of Fe_(3)O_(4)-Au-Ag enhancing Raman spectrum of levofloxacin includes electromagnetic enhancement mechanism,chemical enhancement mechanism,and three enhancement models(mirror model,antenna model,and lightning rod model).This new method is expected to be used in such fields as agriculture,industry,environment,food,medicine,and health,achieving highly sensitive detection of antibiotics in actual samples.

关 键 词：磁性复合纳米材料 Fe_(3)O_(4)-Au-Ag 表面增强拉曼光谱 基底 左氧氟沙星 增强机理 

分 类 号：O657.61[理学—分析化学]