机构地区:[1]四川大学华西医院健康管理中心,四川成都610041 [2]四川大学华西医院心脏内科,四川成都610041
出 处:《中国社会医学杂志》2025年第2期192-195,共4页Chinese Journal of Social Medicine
基 金:四川省医学会高血压疾病(泰阁)专项科研课题(2019TG20)。
摘 要:目的分析老年体检人群冠心病(coronary heart disease,CHD)检出率及其与血糖、血脂的相关性,为提高老年人群CHD预防措施提供依据。方法回顾性分析2021年6月-2024年6月期间成都地区1500例老年体检者的体检结果,记录老年人群CHD检出情况,单因素分析不同临床特征老年人群CHD患病情况,多因素Logistic回归分析导致成都地区老年人群发生CHD的风险因素;依据发生CHD与否,将研究对象分为CHD组和非CHD组,并比较两组血糖、血脂差异;以Spearman相关性检验血糖、血脂与CHD患病的关系。结果1500例成都地区老年体检者中共检出CHD68例,占比4.53%(68/1500),老年体检者男性CHD患病率高于女性,年龄≥80岁人群CHD患病率高于年龄<80岁人群,血糖、血脂异常人群CHD患病率高于血糖、血脂正常人群(P<0.05);回归分析显示,年龄、血糖异常、血脂异常、高血压、饮酒史、吸烟史、CHD家族遗传史为老年体检人群发生CHD的风险因素(P<0.05);Spearman分析结果显示,各血脂(除高密度脂蛋白胆固醇HDL-C外)和血糖指标与成都地区老年人群CHD患病均呈正相关(P<0.05);HDL-C水平与成都地区老年人群CHD患病呈负相关(P<0.05)。结论成都地区老年人群有较高CHD发病率,不同年龄阶段CHD发病率具明显差异,且CHD发病受多种因素(如血糖、血脂异常、高血压等)影响,血糖、血脂异常会增加老年人群CHD发病风险。Objective To analyze the detection rate of coronary heart disease(CHD)in elderly physical examination population in Chengdu area and its correlation with blood glucose and blood lipids.Methods The physical examination results of 1500 elderly people with physical examination in Chengdu area from June 2021 to June 2024 were retrospectively analyzed.The detection of CHD in elderly population was recorded.The prevalence of CHD in elderly population with different clinical characteristics was analyzed by univariate analysis.Multivariat Logistic regression analysis was used to analyze the risk factors of CHD in elderly population in Chengdu.The differences in blood glucose and blood lipids were compared between CHD group and non-CHD group,and Spearman correlation test was adopted to test the relationship between blood glucose,blood lipids and prevalence of CHD.Results A total of 68 cases of CHD were detected in 1500 elderly people with physical examination in Chengdu,accounting for 4.53%(68/1500).The prevalence rate of CHD in males was higher than that in females,the prevalence rate of CHD in people aged≥80 years was higher than that in people aged<80 years,and the prevalence rate of CHD in people with abnormal blood glucose and blood lipids was higher than that in people with normal blood glucose and blood li-pids(P<0.05).Regression analysis indicated that age,abnormal blood glucose,dyslipidemia,hypertension,drinking history,smoking history,and family genetic history of CHD were the risk factors for CHD in elderly physical examination population in Chengdu(P<0.05).Spearman analysis suggested that the levels of various blood lipids[except high-density lipoprotein cholesterol(HDL-C)]and blood glucose indicators were positively correlated with CHD in elderly population in Chengdu(P<0.05).HDL-C level was negatively correlated with CHD in elderly population in Chengdu(P<0.05).Conclusion The prevalence rate of CHD in elderly people in Chengdu is high.The occurrence of CHD is affected by many factors(blood glucose,abnormal
分 类 号:R541.4[医药卫生—心血管疾病] R194.3[医药卫生—内科学]
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