多层螺旋CT腰椎三维后处理技术与定量CT骨密度测定的一致性研究  

Consistency of MSCT 3D processing technique and QCT in measuring BMD for lumbar vertebra

作　　者：李向明 张立新 王卫丰 孔亚群 许晨思 周万博 艾顺生 宋立祥 牛延涛 Li Xiangming;Zhang Lixin;Wang Weifeng;Kong Yaqun;Xu Chensi;Zhou Wanbo;Ai Shunsheng;Song Lixiang;Niu Yantao(Department of Radiology,Beijing Friendship Hospital,Capital Medical University,Beijing 101100,China;Department of Stomatology,Beijing Friendship Hospital,Capital Medical University,Beijing 101100,China;Beijing Subsidiary,Neusoft Medical Systems Co.,Ltd.Beijing 101194,China;Beijing Guangda Hongda Science and Technology Co.Ltd,Beijing 100124,China)

机构地区：[1]首都医科大学附属北京友谊医院放射科,北京101100 [2]首都医科大学附属北京友谊医院口腔科,北京101100 [3]东软医疗系统股份有限公司北京子公司,北京100094 [4]北京光大宏大科技有限公司,北京100124

出　　处：《中国医学装备》2025年第4期28-33,共6页China Medical Equipment

基　　金：国家自然科学基金青年科学基金(82302182)。

摘　　要：目的:研究多层螺旋CT(MSCT)腰椎扫描后处理骨密度(BMD)值与定量CT(QCT)BMD值测试的一致性,探讨临床中MSCT腰椎扫描后处理BMD值应用的可行性。方法:分别选用QRM-ESP145型欧洲脊椎模体(ESP)腰椎、成年羊腰椎和1名志愿者腰椎部位,采用MSCT和QCT设备分别对145型ESP腰椎L2~L4、成年羊腰椎L2~L4和志愿者腰椎L2~L4进行影像扫描。145型ESP腰椎L2~L4和羊腰椎骨L2-L4由MSCT与QCT各扫描3次测量BMD值,志愿者腰椎L2~L4按临床检查标准各扫描1次,分别重建3次取BMD平均值。设QCT扫描BMD值为对照组,MSCT扫描BMD值为实验组,根据实验可靠性又将实验组分为实验1组(腰椎2D局部区域体积BMD后处理)和实验2组(腰椎3D整体体积BMD后处理)。对比分析3组MSCT 3D腰椎扫描后处理BMD值与QCT测试BMD值的一致性。结果:MSCT 3D腰椎后处理3组145型ESP腰椎L2~L4的BMD值分别为(120.83±0.97)、(199.57±0.54)和(119.19±1.04)mg/cm^(3);羊腰椎骨L2~L4的BMD值分别为(414.89±1.72)、(410.50±0.77)和(420.25±2.71)mg/cm^(3),志愿者腰椎L2-L4的BMD值分别为(141,22±0.09)、(137.38±0.37)和(152.03±1.03)mg/cm^(3),与QCT检查BMD值比较,差异均无统计学意义(P>0.05)。结论:腰椎MSCT3D后处理BMD与QCT数值具有高度一致性,其后处理技术可替代QCT进行BMD检查,并能够减少受检者不必要的辐射和检查费用。Objective:To study the consistency between post-processing bone mineral density(BMD)values of multi-slice spiral computed tomography(MSCT)scan and the BMD value of quantitative computed tomography(QCT)for lumbar vertebra,so as to explore the feasibility of utilizing MSCT scan-based post-processing BMD values for lumbar vertebra in clinical practice.Methods:The MSCT equipment and QCT equipment were respectively adopted to conduct imaging scan for the L2-L4 of lumber vertebra of QRMESP145 European Spine Phantom(ESP),and L2-L4 of lumbar vertebra of adult sheep,and L2-L4 of lumbar vertebra of adult volunteer.The L2-L4 of ESP lumber vertebra and L2-L4 of lumbar vertebra of adult sheep were scanned respectively MSCT and QCT for three times,so as to measure BMD values.The L2-L4 of lumbar vertebrae of volunteers were scanned respectively by the two methods for one time according to the standard of clinical examination,which were reconstructed by three times so as to obtain mean of them.The BMD values of QCT scan were set as control group,and the BMD values of MSCT scan were set as experiment group.The experiment group was further divided into experiment 1 group[two dimension(2D)regional volumetric BMD values of the lumbar vertebra]and experiment 2 group[three dimension(3D)global volumetric BMD post-processing of the lumbar vertebra]according to the reliability of experiment.Then,the consistency between the MSCT 3D post-processing BMD values of three groups and QCT-measured BMD values was compared and analyzed.Results:The MSCT 3D post-processing BMD values of L2-L4 of ESP lumbar vertebra of three groups were respectively(120.83±0.97),(199.57±0.54)and(119.19±1.04)mg/cm³,and that of L2-L4 of lumbar vertebra of adult sheep of three groups were respectively(414.89±1.72),(410.50±0.77)and(420.25±2.71)mg/cm^(3),and that of L2-L4 of lumbar vertebra of volunteer were respectively(141.22±0.09),(137.38±0.37)and(152.03±1.03)mg/cm^(3).There were not statistically significant differences in BMD values between MSCT examination

关 键 词：多层螺旋CT(MSCT) 定量CT(QCT) 腰椎三维后处理技术 骨密度(BMD) 测量体模(CP) 

分 类 号：R814.3[医药卫生—影像医学与核医学]