3.0T磁共振弥散加权成像表观弥散系数值对老年急性胰腺炎患者疾病严重程度评估价值分析  

Analysis on the assessment value of 3.0T MR DWI-ADC for the disease severity of elderly patients with acute pancreatitis

作　　者：丛黎 周华亭 李文文 Cong Li;Zhou Huating;Li Wenwen(Department of Radiotherapy,Weihai Hospital of Traditional Chinese Medicine,Weihai 264200,China)

机构地区：[1]威海市中医院放射科,威海264200

出　　处：《中国医学装备》2025年第4期39-42,共4页China Medical Equipment

摘　　要：目的:探究3.0T磁共振(MR)弥散加权成像(DWI)表观弥散系数(ADC)值对老年急性胰腺炎(AP)患者疾病严重程度评估价值。方法:回顾性选取2023年8月至2024年9月期间威海市中医院收治的68例老年AP患者纳入病例组,另选40名健康者作为健康对照组,病例组按照病情严重程度再分为轻中度组(35例)和重度组(33例)。对比各组ADC值、快速扩散ADC分数(Ft ADC)值,采用受试者工作特征(ROC)曲线评价ADC值对AP患者病情严重程度的预测价值。结果:健康对照组、轻中度组和重度组的ADC值、Ft ADC值对比,差异均有统计学意义(F=30.821、23.145,P<0.05),ADC值由高到低依次为:重度组(0.92±0.24)>轻中度组(0.86±0.23)>健康对照组(0.58±0.12),Ft ADC值由高到低依次为:对照组(0.59±0.18)>轻中度组(0.45±0.15)>重度组(0.35±0.11)。ADC值联合Ft ADC诊断疾病严重程度的准确率、灵敏度、特异度分别为93.33%、96.23%和90.38%,准确率、灵敏度显著高于单一ADC值的82.86%、75.47%以及单一Ft ADC值的85.71%、84.91%。结论:随着急性胰腺炎严重程度的增加,ADC值逐渐降低,而Ft ADC值逐渐升高,ADC值联合Ft ADC对疾病严重程度的诊断效能明显高于单一指标的诊断。ADC值和Ft ADC联合应用有助于提高老年AP患者病情严重程度的评估准确性,能够为临床治疗和疾病管理提供重要依据。Objective:To explore the assessment value of 3.0T magnetic resonance(MR)diffusion weighted imaging(DWI)-apparent diffusion coefficient(ADC)on disease severity in elderly patients with acute pancreatitis(AP).Methods:A total of 68 elderly AP patients who admitted to Weihai Hospital of Traditional Chinese Medicine from August 2023 to September 2024 were retrospectively selected,and they were enrolled in cases group,and 40 healthy persons were included in healthy control group.According to the disease severity,the cases group were divided further into mild-moderate group(n=35)and severe group(n=33).The ADC value and fast diffusion ADC(Ft ADC)fraction of all groups were compared,and receiver operating characteristic(ROC)curve was adopted to evaluate the predictive value of ADC value on the disease severity of AP patients.Results:There were significant differences in ADC values and Ft ADC values among healthy control group,mild-moderate group and severe group(F=30.821,23.145,P<0.05).The orders of ADC values were as follows from high to low:severe group(0.92±0.24)>mild-moderate group(0.86±0.23)>control group(0.58±0.12).The orders of Ft ADC values were as follows from high to low:healthy control group(0.59±0.18)>mild-moderate group(0.45±0.15)>severe group(0.35±0.11).The accuracy,sensitivity and specificity of ADC value combined with Ft ADC value were respectively 93.33%,96.23%and 90.38%in diagnosing disease severity.The accuracy and sensitivity of the combined examination were respectively higher than 82.86%and 75.47%of single ADC value,and were respectively higher than 85.71%and 84.91%of single Ft ADC value.Conclusion:With the increasing of disease severity of acute pancreatitis,ADC value gradually decreased,while Ft ADC value gradually increased.The diagnostic efficiency of the combination of ADC value and Ft ADC value for the disease severity were significantly higher than that of single indicator.Therefore,the combined application of ADC value and Ft ADC can help to improve the assessment accuracy for the disea

关 键 词：磁共振(MR) 弥散加权成像(DWI) 表观弥散系数(ADC)值 老年急性胰腺炎 疾病严重程度 

分 类 号：R445.2[医药卫生—影像医学与核医学]