滇西地区静脉用药调配中心工作人员抗肿瘤药物职业暴露及防护的调查研究  

Investigation on Occupational Exposure and Protection of the PIVAS Staff Exposed to Antineoplastic Drugs in Western Yunnan

作　　者：肖杉蕊 李霞 邱琳 刘全义 谢雨璇 古云 Xiao Shanrui;Li Xia;Qiu Lin;Liu Quanyi;Xie Yuxuan;Gu Yun(College of Pharmacy,Dali University,Dali,Yunnan 671000,China;Pharmacy Intravenous Admixture Service,The First Affiliated Hospital of Dali University,Dali,Yunnan 671000,China)

机构地区：[1]大理大学药学院,云南大理671000 [2]大理大学第一附属医院静脉用药调配中心,云南大理671000

出　　处：《大理大学学报》2025年第4期21-26,共6页Journal of Dali University

基　　金：云南省教育厅科学研究基金项目(2024J0851);大理市科技计划项目(2024KBG028)。

摘　　要：目的:了解云南省滇西地区医疗机构静脉用药调配中心(PIVAS)工作人员抗肿瘤药物(ADs)职业暴露基本情况,旨在为医疗机构加强PIVAS中ADs的管理提供科学依据。方法:采用德尔菲专家函询法确定问卷内容,通过问卷星平台对云南省滇西地区9所三级综合医院PIVAS工作人员进行问卷调查。结果:212名PIVAS工作人员职业接触ADs总时长基本以短期接触为主,其中部分工作人员对ADs职业暴露的个人防护和处置方式不规范,职业接触ADs的不良结局主要为脱发(占56.60%);97.17%的工作人员接受了ADs调配岗前规范化培训和考核,92.92%的工作人员能接受培训方式、内容和结果,72.64%的PIVAS工作人员所在医院已经建立了ADs职业暴露防护制度,培训周期主要是6~12个月(占62.74%)。结论:PIVAS工作人员对ADs职业暴露的认知及防护存在不足,医疗机构应建立和完善职业防护管理制度,加强规范化培训和考核,提高PIVAS工作人员职业防护意识,以促进职业健康发展。Objective:To investigate the basic situation of occupational exposure to antineoplastic drugs(ADs)among the staff in the pharmacy intravenous admixture service(PIVAS)of medical institutions in western Yunnan,and to provide scientific basis for medical institutions to strengthen the management of ADs in PIVAS.Methods:The questionnaire content was determined by Delphi expert inquiry method,and the PIVAS staff in 9 tertiary general hospitals in western Yunnan was investigated by Wenjuanxing platform.Results:The total duration of occupational exposure to ADs of 212 PIVAS staff was mainly short-term exposure,and some of them had irregular personal protection and disposal methods for occupational exposure to ADs.The adverse outcome of occupational exposure to ADs was mainly hair loss(accounted for 56.60%).97.17%of the staff had received standardized pre-job training and assessment before ADs deployment.92.92%of the staff can accept the training methods,contents and results.72.64%of PIVAS staff's hospitals had established ADs occupational exposure protection system.The training period was mainly six months to twelve months(account for 62.74%).Conclusion:PIVAS staff has insufficient cognition and protection of occupational exposure to ADs.Medical institutions should establish and improve the occupational protection management system,strengthen standardized training and assessment,and improve the occupational protection awareness of PIVAS staff to promote occupational health development.

关 键 词：德尔菲法 静脉用药调配中心 抗肿瘤药物 职业暴露 问卷调查 

分 类 号：R979.1[医药卫生—药品]