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作 者:王淑慧 梁鸿[1] 张庆英[1] 张国武 屠鹏飞[1] WANG Shuhui;LIANG Hong;ZHANG Qingying;ZHANG Guowu;TU Pengfei(State Key Laboratory of Natural and Biomimetic Drugs/School of Pharmaceutical Sciences,Peking University,Beijing 100191,China;Shangri-La Tianquan Chuanbei Technology Co.,Ltd.,Shangri-La 674401,China)
机构地区:[1]北京大学药学院/天然药物及仿生药物国家重点实验室,北京100191 [2]香格里拉市天泉川贝科技有限公司,云南香格里拉674401
出 处:《中国现代中药》2025年第4期593-600,共8页Modern Chinese Medicine
基 金:国家自然科学基金青年基金项目(82304690);中国博士后科学基金第17批特别资助项目(2024T170038)。
摘 要:川贝母是著名的止咳要药,临床疗效明确,市场需求量大,但由于特殊的生境和过度的采挖,其野生资源已濒临枯竭。因此,发展栽培川贝母产业是解决临床用药和市场需求最有效的途径,同时也能保护野生资源,确保中药产业可持续发展,增加高原地区居民收入。川贝母人工栽培历史较短且栽培难度大,存在种质混杂、栽培变异和性状差异大等问题,严重制约了川贝母栽培产业的发展。为推动栽培川贝母产业高质量发展,对川贝母资源现状和影响栽培川贝母品质的生态环境、种质资源、繁育方式、栽培管理及采收加工等生产技术方面的研究进展进行综述,提出建立川贝母各基原植物野生抚育基地、规范化栽培模式和标准、工业化产地加工体系和全程生产质量管理体系等建议,以期为栽培川贝母生产技术的提升和产业可持续发展提供参考。Fritillaria Cirrhosae Bulbus is a renowned Chinese herbal medicine with definite cough-relieving effect and has a high market demand.The wild resources of Fritillaria Cirrhosae Bulbus have been gradually declining due to specific habitat requirements and over-exploitation.The cultivation of Fritillaria Cirrhosae Bulbus emerges as a crucial strategy to fulfill clinical needs,satisfy the market demand,conserve wild resources,ensure the sustainable development of the Chinese medicine industry,and enhance the income of residents in high-altitude regions.Nonetheless,the artificial cultivation of Fritillaria Cirrhosae Bulbus has a short history and faces several challenges.Issues such as germplasm confounding,variation occurrence in cultivation,and morphological discrepancies hinder the advancement of the Fritillaria Cirrhosae Bulbus cultivation industry.To promote the development of high-quality and high-yield Fritillaria Cirrhosae Bulbus cultivation,this paper reviews the current status of Fritillaria Cirrhosae Bulbus resources and the research progress in the eco-environments,germplasm resources,breeding methods,cultivation management,harvesting,and processing,all of which impact the quality of Fritillaria Cirrhosae Bulbus.Furthermore,recommendations are proposed,including establishing a wild tending base,a standardized cultivation model and standards,an industrial production area processing system,and a comprehensive production quality management system for each original plant of Fritillaria Cirrhosae Bulbus.These suggestions aim to provide a reference for the sustainable development of the high-quality and high-yield Fritillaria Cirrhosae Bulbus industry.
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