关于骨髓型外照射急性放射病的探索与实践  

Exploration and practice of bone marrow form of acute radiation sickness from external exposure

作　　者：王鑫淼 何光翠 易海 WANG Xinmiao;HE Guangcui;YI Hai(The General Hospital of Western Theater of the People′s Liberation Army,Chengdu 610083)

机构地区：[1]中国人民解放军西部战区总医院,成都610083

出　　处：《辐射防护通讯》2025年第2期39-41,共3页Radiation Protection Bulletin

基　　金：西部战区总医院院管课题(2024-YGLC-A03)。

摘　　要：骨髓是电离辐射(IR)敏感器官,短时间内暴露于一定剂量的IR会导致骨髓造血系统损伤,引起机体白细胞和血小板快速降低,严重的会因出血和感染而死亡。造血干细胞移植(HSCT)是IR暴露引起的骨髓型急性放射病(ARS)专科救治中的重要技术,但是目前可供参考的实际治疗案例极为罕见。为提高ARS患者救治能力,本单位就应用HSCT救治ARS进行了一定的研究与探索,旨在进一步积累相关的经验与技术。Bone marrow is an ionizing radiation(IR)sensitive organ and short-term exposure to a certain dose of IR could cause damage to hematopoietic system,resulting in rapid decrease in white blood cells and platelets.In severe cases,IR may lead death due to serious bleeding and infection.Hematopoietic stem cell transplantation(HSCT)is important specialist treatment technology in bone marrow form of acute radiation sickness(ARS)from external IR.However,there are currently very few actual rescue cases available for reference.In order to improve the treatment ability of ARS patients,some research and exploration on the application of HSCT in the therapy of ARS were carried out,so as to further accumulate experience and technology related to the management of ARS.

关 键 词：电离辐射 急性放射病 放射损伤 造血干细胞移植 全骨髓放疗 

分 类 号：R818.05[医药卫生—放射医学]