四川某医院2022年—2023年皮肤和软组织感染患者病原菌特征及耐药情况分析  

Analysis of Pathogen Bacteria Characteristics and Drug Resistance in Patients with Skin and Soft Tissue Infection in a Hospital in Sichuan Province from 2022 to 2023

作　　者：庄化迪 赵菊花 Zhuang Hua-di;Zhao Ju-hua(Department of Dermatology,Nanchong Central Hospital,Nanchong Sichuan 637000)

机构地区：[1]四川省南充市中心医院皮肤科,四川南充637000

出　　处：《国外医药(抗生素分册)》2025年第2期121-125,共5页World Notes on Antibiotics

摘　　要：目的 探讨及分析四川某医院2022年—2023年皮肤和软组织感染(SSTI)患者病原菌特征及耐药情况,为当地SSTI的诊治及合理用药提供一定的理论依据和技术支持。方法 采用回顾性分析,收集2022年1月—2023年12月在四川某医院收治的皮肤及软组织感染患者的性别、年龄等基本信息,同时收集分离培养的病原菌种类及药敏试验结果。使用WHONET 5.6和SPSS24.0软件进行数据的录入和整理。年龄采用中位数表示,计数资料采用频数和百分比表示。结果 本研究共纳入86例研究对象,共培养出病原菌92株,其中,革兰阳性菌56株(60.87%),以金黄色葡萄球菌(48.20%)为主;革兰阴性菌36株(39.13%),以大肠埃希菌(36.11%)为主。葡萄球菌属对奎奴普汀/达福普汀、万古霉素、利奈唑胺和替加环素的耐药率均为0;大肠埃希菌和肺炎克雷伯菌对厄他培南和亚胺培南的耐药率均为0。结论 针对SSTI患者,应根据临床症状及药敏结果选择针对性的治疗方案是控制感染的关键。Objective In order to offer a theoretical foundation and technical support for the diagnosis,treatment,and sensible use of skin and soft tissue infections(SSTI)in the local community,it is necessary to examine the pathogen features and medication resistance in patients with SSTI in a hospital in Sichuan province between 2022 and 2023.Methods A retrospective study was conducted to collect basic information on the gender and age of SSTI patients admitted to a hospital in Sichuan from January 2022 to December 2023.At the same time,the types of pathogens were isolated and cultured and the results of drug sensitivity tests were collected.Use WHONET 5.6 and SPSS 24.0 software to input and organize data.Age is represented by a median,while count data is represented by frequency and percentage.Results This study included 86 patients with SSTI,and 92 strains of the pathogen were isolated.Of these,56 were Gram positive bacteria(60.87%),with Staphylococcus aureus accounting for 48.20 percent of the pathogens;36 were Gram negative bacteria(39.13%),with Escherichia coli accounting for 36.11 percent of the pathogens.Both Klebsiella pneumoniae and Escherichia coli have zero resistance rates to imipenem and ertapenem.The resistance rates of Escherichia coli and Klebsiella pneumoniae to ertapenem and imipenem were both 0.Conclusion For SSTI patients,the key to controlling infection is to select a targeted treatment plan according to clinical symptoms and drug sensitivity results.

关 键 词：皮肤感染 软组织感染 病原菌 抗菌谱 合理用药 

分 类 号：R978.1[医药卫生—药品]