快速现场评价技术在介入呼吸病学中的应用进展  

Rapid on-site evaluation technology and its application advancements in interventional pulmonology

作　　者：朱芷若 王瑶辉 肖云[2,3,4,5] 周锐[2,3,4,5] 肖奎[2,3,4,5] Zhu Zhiruo;Wang Yaohui;Xiao Yun;Zhou Rui;Xiao Kui(Department of Pulmonary and Critical Care Medicine,the Fourth Hospital of Changsha,Hunan Changsha 410006;Department of Pulmonary and Critical Care Medicine,the Second Xiangya Hospital,Central South University,Central South University,Hunan Changsha 410011,China;Research Unit of Respiratory Disease,Central South University,Central South University,Hunan Changsha 410011,China;Clinical Medical Research Center for Resipratory and Critical Care Medicine of Hunan Province,Central South University,Hunan Changsha 410011,China;Diagnosis and Treatment Center of Respiratory Disease,Central South University,Hunan Changsha 410011,China)

机构地区：[1]长沙市第四医院呼吸与危重症医学科,湖南长沙410006 [2]中南大学湘雅二医院呼吸与危重症医学科,湖南长沙410011 [3]中南大学中南大学呼吸疾病研究所,湖南长沙410011 [4]中南大学湖南省呼吸与危重症疾病临床医学研究中心,湖南长沙410011 [5]中南大学中南大学呼吸疾病诊疗中心,湖南长沙410011

出　　处：《中华介入放射学电子杂志》2025年第1期7-13,共7页Chinese Journal of Interventional Radiology:electronic edition

基　　金：湖南省自然科学基金(2021JJ30963);湖南省卫生健康委科研计划(202103020704);国家临床重点专科项目。

摘　　要：快速现场评价(rapid on-site evaluation,ROSE)技术是在取样现场对穿刺活检标本或刷检标本进行快速染色及显微镜观察后由专业人员现场评价判断以获得初步诊断的一种实时病理学技术,并可根据所获得的初步诊断来制定优先策略,进而反馈指导下一步操作。随着内镜技术及细针穿刺技术的高速发展,在活检和穿刺现场对活检标本快速染色观察的ROSE 技术也得以蓬勃发展,尤其在介入呼吸病学中被广泛应用。ROSE 在呼吸介入诊疗操作中的应用主要是联合经支气管针吸活检术、经支气管肺活组织检查、超声引导下经支气管针吸活检、经支气管超声导向鞘引导的经支气管肺活检术等支气管镜操作,其次是其联合应用于经胸壁肺穿刺活检及联合应用于内科胸腔镜检查。文章对ROSE技术的起源、发展、分类、操作过程以及其在呼吸介入诊疗操作中的应用进展等方面进行综述。Rapid on-site evaluation(ROSE)technology is a real-time pathological technique that involves rapid staining and microscopic observation of biopsy or brush specimens at the sampling site,followed by on-site evaluation and judgment by expert to obtain preliminary diagnosis.Based on the preliminary ROSE diagnosis,priority strategies can be formulated to provide feedback and guide the next step of operation.With the rapid development of endoscopic technology and fine needle aspiration technology,ROSE technology which can quickly stain and observe biopsy specimens on site has also flourished,especially in interventional pulmonology.The application of ROSE in interventional pulmonology diagnosis and treatment mainly involve the combination of transbronchial needle aspiration(TBNA),transbronchial lung biopsy(TBLB),endobronchial ultrasound guided transbronchial needle aspiration(EBUS-TBNA),endobronchial ultrasonography with guide sheath transbronchus lung biopsy(EBUS-GSTBLB)and other bronchoscopic procedures.Other applications of ROSE in interventional pulmonology include percutaneous lung biopsy and medical thoracoscopy.This review specifically elaborate on the origin,development,classification,operational process,and recent advances of ROSE technology in interventional pulmonology.

关 键 词：快速现场评价 快速现场评价技术 介入呼吸病学 

分 类 号：R56[医药卫生—呼吸系统]