无水乙醇联合Glubran-2胶治疗PuigⅢ型静脉畸形的疗效分析  

Analysis of the therapeutic effect of anhydrous ethanol combined with Glubran-2 glue in the treatment of Puig typeⅢvenous malformation

作　　者：刘浪 蒋贻洲 庞宁东 姜华 牛传强 刘录 张靖 李海波 Liu Lang;Jiang Yizhou;Pang Ningdong;Jiang Hua;Niu Chuanqiang;Liu Lu;Zhang Jing;Li Haibo(Department of Interventional Radiology&Vascular Anomalies,Guangzhou Women and Children's Medical Center,Guangzhou Medical University,Guangdong Guangzhou 510627;Department of Minimally Invasive Intervention,Guangdong Academy of Medical Sciences,Guangdong Provincial People's Hospital,Guangdong Guangzhou 510080,China)

机构地区：[1]广州医科大学附属妇女儿童医疗中心介入血管瘤科,广东广州510627 [2]广东省人民医院(广东省医学科学院)微创介入科,广东广州510080

出　　处：《中华介入放射学电子杂志》2025年第1期44-48,共5页Chinese Journal of Interventional Radiology:electronic edition

基　　金：广州市科技计划项目(2023A03J0923)。

摘　　要：目的探讨无水乙醇联合Glubran-2胶治疗PuigⅢ型静脉畸形的方法,评价其临床疗效及安全性。方法回顾性分析2019年1月至2022年1月在广州医科大学附属妇女儿童医疗中心介入血管瘤科收治的76例PuigⅢ型静脉畸形患者的临床资料。选用无水乙醇联合Glubran-2胶经皮局部治疗静脉畸形患者。76例患者中男性35例,女性41例,年龄3~16岁(中位年龄7岁)。随访时间25~67个月(中位随访时间47个月)。结果76例患者共接受局部治疗次数1~3次,平均(2.69±0.61)次。至随访期结束43例治愈、26例明显缓解、4例部分缓解,3例无效。所有患者均有术后一过性病灶肿胀,出现术后血尿4例,局部张力性水泡3例,未发生皮肤破溃及异位栓塞等严重并发症。结论无水乙醇联合Glubran-2胶治疗PuigⅢ型静脉畸形操作简便、安全可靠、并发症少。Objective To explore the method of using anhydrous ethanol combined with Glubran-2 gel to treat Puig typeⅢvenous malformation,and evaluate its clinical efficacy and safety.Methods The clinical data of 76 patients with Puig typeⅢvenous malformation admitted to our hospital from January 2019 to January 2022 were retrospectively analyzed.The treatment of venous malformations was all percutaneous local treatment,using anhydrous ethanol combined with Glubran-2 glue.Among the 76 patients,there were 35 males and 41 females,aged 3-16 years(median age:7 years).The follow-up period ranged from 25 to 67 months(median follow-up time was 47 months).Results The 76 patients recived local treatment for 1-3 times,with an average of(2.69±0.61)times.By the end of the follow-up period,43 cases were cured,26 cases showed significant relief,4 cases showed partial relief,and 3 cases were ineffecive.All patients had transient swelling of the lesion after surgery,with 4 cases of postoperaive hematuria and 3 cases of local tension blisters.No serious complications such as skin ulceration or ectopic embolism occurred.Conclusion The combination of anhydrous ethanol and Glubran-2 glue for the treatment of Puig typeⅢvenous malformation is simple,safe,and reliable,with fewer complications.

关 键 词：静脉畸形 无水乙醇 Glubran-2胶 

分 类 号：R654.3[医药卫生—外科学]