梅尼埃病患者症状表现及其对生活质量的影响  

Symptoms and impact on quality of life of patients with Ménière′s disease

作　　者：赵艳丽 曹雪娇 张冬梅 蒋成芳 王武庆 吴沛霞[1,2,4] Zhao Yanli;Cao Xuejiao;Zhang Dongmei;Jiang Chengfang;Wang Wuqin;Wu Peixia(School of Nursing,Fudan University,Shanghai 200032,China;Nursing Department,Eye and ENT Hospital of Fudan University,Shanghai 200031,China;Otology Center,Department of Otolaryngology,Eye and ENT Hospital of Fudan University,Shanghai 200031,China;Dizziness and Balance Disorders Clinical Center,Eye and ENT Hospital of Fudan University,Shanghai 200031,China)

机构地区：[1]复旦大学护理学院,上海200032 [2]复旦大学附属眼耳鼻喉科医院护理部,上海200031 [3]复旦大学附属眼耳鼻喉科医院耳鼻喉科耳科中心,上海200031 [4]复旦大学附属眼耳鼻喉科医院眩晕与平衡障碍临床中心,上海200031

出　　处：《中华耳鼻咽喉头颈外科杂志》2025年第3期305-312,共8页Chinese Journal of Otorhinolaryngology Head and Neck Surgery

基　　金：国家重点研发计划“常见多发病防治研究”重点专项(2023YFC2508000)。

摘　　要：目的探讨梅尼埃病患者的症状表现及其对生活质量的影响。方法采用横断面研究方法,研究对象为2014年10月至2022年12月就诊于复旦大学附属眼耳鼻喉科医院耳鼻喉科门诊的梅尼埃病患者,应用中文版梅尼埃病结局问卷(Ménière′s Disease Outcomes Questionnaire,MDOQ)、梅尼埃病特异症状检查表进行调查。应用SPSS 25.0软件,采用多重线性回归分析梅尼埃病症状对患者生活质量的影响。结果最终共纳入790例梅尼埃病患者,其中男性418例、女性372例,年龄(54.8±13.1)岁,确诊时长0~72个月,中位时间3个月。中文版MDOQ总分为(61.0±12.0)分,入组患者症状表现包括听力变化、耳鸣、耳闷感、跌倒发作、眩晕发作、视觉不稳、头晕、头痛等。多重线性回归分析显示,年龄、耳鸣情况、耳闷感、跌倒发作次数、视觉不稳、头晕及头痛是影响梅尼埃病患者生活质量的显著因素(F=145.50,P<0.05)。结论梅尼埃病患者生活质量有待改善,关注梅尼埃病特异性症状及其对患者生活质量的影响,并基于此开展针对性的症状干预将成为今后疾病管理的重点。ObjectiveTo explore the symptoms of Ménière′s disease patients and their impact on quality of life.MethodsA cross-sectional study was conducted,consecutively enrolling patients of Ménière′s disease who visited the Otolaryngology Clinic at the Eye&ENT Hospital of Fudan University from October 2014 to December 2022.The Chinese version of the Ménière′s Disease Outcomes Questionnaire(MDOQ)and a Ménière′s disease-specific symptom checklist were utilized for assessment.SPSS 25.0 software was employed to perform multiple linear regression analysis to determine the impact of Ménière′s disease symptoms on patients′quality of life.ResultsA total of 790 patients with a definitive diagnosis of Ménière′s disease who met the inclusion and exclusion criteria were analyzed.The cohort comprised 418 males and 372 females,with a mean age of(54.8±13.1)years and a diagnosis duration ranging from 0 to 72 months,with a median of 3 months.The total score of the Chinese MDOQ was 61.0±12.0.The symptomatic presentations of the enrolled patients included hearing changes,tinnitus,aural fullness,drop attacks,vertigo episodes,visual instability,dizziness,and headache.Multiple linear regression analysis revealed that age,tinnitus,aural fullness,frequency of drop attacks,visual instability,dizziness,and headache were significant factors affecting the quality of life in Ménière′s disease patients(F=145.50,P<0.05).ConclusionsThe quality of life in Ménière′s disease patients requires improvement.Attention to the specific symptoms of Ménière′s disease and their impact on patients′quality of life,along with targeted symptom interventions based on these findings,will be a focal point in future disease management.

关 键 词：梅尼埃病 体征和症状 生活质量 问卷调查 

分 类 号：R764.33[医药卫生—耳鼻咽喉科]