疏肝健脾化浊法在冠心病心律失常中的应用  

Application of the method of soothing the liver,strengthening the spleen,and eliminating turbidity in the treatment of arrhythmia in coronary heart disease

作　　者：贾鲁姣 权欢欢 夏艳斐 JIA Lujiao;QUAN Huanhuan;XIA Yanfei(Department of Cardiovascular Medicine,Pingdingshan Second People′s Hospital,Pingdingshan 467000,China;Department of Cardiovascular Medicine,Pingdingshan Traditional Chinese Medicine Hospital,Pingdingshan 467000,China)

机构地区：[1]平顶山市第二人民医院心血管内二科,平顶山467000 [2]平顶山市中医医院心血管内科,平顶山467000

出　　处：《华夏医学》2025年第2期79-84,共6页Acta Medicinae Sinica

基　　金：2024年度河南省中医药科学研究专项课题(2024ZY3114)。

摘　　要：目的观察疏肝健脾化浊法治疗冠心病心律失常的临床效果。方法选取115例冠心病心律失常患者作为研究对象,按照随机数字表法分为常规组和中医组。常规组实施常规西医治疗,中医组在常规组的治疗基础上,联合实施舒肝健脾化浊法治疗,比较两组患者的临床证候积分、不良情绪评分、睡眠情况、心功能指标及主要心血管不良事件(MACE)发生情况。结果在不同治疗方案下,中医组的心悸胸闷、头晕易疲、面色萎黄、腹胀纳差等证候积分均低于常规组,差异具有统计学意义(P<0.05);中医组的汉密顿焦虑量表(HAMA)、汉密顿抑郁量表(HAMD)、匹兹堡睡眠质量指数(PSQI)评分均低于常规组(P<0.05);中医组的左室射血分数(LVEF)高于常规组,左心室舒张末期容积(LVEDV)、左心室收缩末期容积(LVESV)、B型脑利钠肽(BNP)的测得值均低于常规组(P<0.05);中医组的MACE发生率低于常规组(P<0.05)。结论疏肝健脾化浊法辅助治疗冠心病心律失常能改善患者临床证候,对调节患者不良情绪、促进心功能恢复并降低MACE发生风险均有积极意义。Objective To observe the clinical effect of the method of soothing the liver,strengthening the spleen,and eliminating turbidity in the treatment of arrhythmia in coronary heart disease.Methods 115 patients with coronary heart disease and arrhythmia were selected as the research subjects and randomly divided into the conventional group and traditional Chinese medicine group according to the random number table method.The conventional group were received conventional Western medicine treatment,while the traditional Chinese medicine group were received conventional treatment combined with the method of soothing the liver,strengthening the spleen,and eliminating turbidity.The clinical syndrome scores,adverse emotion scores,sleep conditions,cardiac function indicators,and the occurrence of major adverse cardiac events(MACE)were compared between the two groups.Results Under different treatment plans,the scores of symptoms such as palpitations,chest tightness,dizziness,fatigue,pale complexion,abdominal distension,and poor appetite in the traditional Chinese medicine group were lower than those in the control group,and the difference was statistically significant(P<0.05).The Hamilton Anxiety Scale(HAMA),Hamilton Depression Scale(HAMD),and Pittsburgh Sleep Quality Index(PSQI)scores in the traditional Chinese medicine group were lower than those in the control group(P<0.05).The left ventricular ejection fraction(LVEF)of the traditional Chinese medicine group was higher than that of the conventional group,while left ventricular end-diastolic volume index(LVEDV),left ventricular and systolic volume(LVESV),and B-type natriuretic peptide(BNP)were all lower than those of the conventional group(P<0.05).The incidence of MACE in the traditional Chinese medicine group was lower than that in the conventional group(P<0.05).Conclusion The auxiliary treatment of coronary heart disease arrhythmia with the method of soothing the liver,strengthening the spleen,and eliminating turbidity can improve the clinical symptoms of patients,regulat

关 键 词：冠心病心律失常 疏肝健脾化浊法 双心疾病 心功能 主要心血管不良事件 

分 类 号：R54[医药卫生—心血管疾病]