应急性宫颈环扎术治疗体外受精-胚胎移植双胎妊娠合并宫颈机能不全的效果  

Effect of acute cervical cerclage in the treatment of twin pregnancy complicated with cervical incompetence after in vitro fertilization-embryo transfer

作　　者：黄珍 王燕枚 刘帅婷 刘素梅 陈彬 HUANG Zhen;WANG Yanmei;LIU Shuaiting;LIU Sumei;CHEN Bin(Department of Gynecology,Ganzhou Maternal and Child Health Care Hospital,Jiangxi Province,Ganzhou 341000,China)

机构地区：[1]江西省赣州市妇幼保健院妇科,江西赣州341000

出　　处：《中国当代医药》2025年第11期69-72,共4页China Modern Medicine

基　　金：江西省卫生健康委科技计划项目(202312009)。

摘　　要：目的探讨应急性宫颈环扎术治疗体外受精-胚胎移植(IVF-ET)双胎妊娠合并宫颈机能不全(CI)的效果。方法回顾性分析2022年1月至2024年1月赣州市妇幼保健院收治的66例IVF-ET双胎妊娠合并CI患者的临床资料,按照治疗方式分为观察组与对照组,每组各33例,观察组采用应急性宫颈环扎术治疗,对照组采用保守期待治疗。比较两组的妊娠结局及新生儿情况。结果两组的妊娠结局比较,差异有统计学意义(P<0.05)。在两组≥35周正常分娩及<35周早产的产妇中,观察组的分娩孕龄为(34.57±3.95)周,长于对照组的(31.36±4.10)周,差异有统计学意义(P<0.05)。观察组≥35周正常分娩的新生儿出生体重为(2.29±0.67)kg,高于对照组的(1.82±0.75)kg,差异有统计学意义(P<0.05);观察组≥35周正常分娩的新生儿及<35周早产儿的5 min Apgar评分高于对照组,且新生儿窒息率、围生儿死亡率均低于对照组,差异有统计学意义(P<0.05)。结论相对保守期待治疗而言,应急性宫颈环扎术在IVF-ET术后双胎妊娠合并CI患者中更有利于延长孕龄,提高新生儿存活率,值得临床推广。Objective To investigate the effect of acute cervical cerclage in the treatment of twin pregnancy complicated with cervical incompetence(CI)after in vitro fertilization-embryo transfer(IVF-ET).Methods The clinical data of 66 patients with IVF-ET twin pregnancy complicated with CI admitted to Ganzhou Maternal and Child Health Care Hospital from January 2022 to January 2024 were retrospectively analyzed.According to the treatment methods,they were divided into observation group and control group,with 33 cases in each group.The observation group was treated with acute cervical cerclage,and the control group was treated with conservative expectant treatment.The pregnancy outcomes and neonatal conditions were compared between the two groups.Results There was statistically significant difference in pregnancy outcome between the two groups(P<0.05).Among the normal delivery women≥35 weeks and premature delivery women<35 weeks in the two groups,the gestational age of delivery in the observation group was(34.57±3.95)weeks,which was longer than(31.36±4.10)weeks in the control group,and the difference was statistically significant(P<0.05).The birth weight of normal delivery newborns≥35 weeks in the observation group was(2.29±0.67)kg,which was higher than(1.82±0.75)kg in the control group,and the difference was statistically significant(P<0.05).The 5 min Apgar score of normal delivery neonates≥35 weeks and premature infants<35 weeks in the observation group was higher than that in the control group,and the neonatal asphyxia rate and perinatal mortality rate were lower than those in the control group,and the differences were statistically significant(P<0.05).Conclusion Compared with conservative expectant treatment,acute cervical cerclage is more conducive to prolong gestational age and improve neonatal survival rate in twin pregnancy with CI after IVF-ET,which is worthy of clinical promotion.

关 键 词：体外受精-胚胎移植 双胎妊娠 宫颈机能不全 期待治疗 应急性宫颈环扎术 妊娠结局 新生儿情况 

分 类 号：R714[医药卫生—妇产科学]