优化静脉铁剂输注管理策略与探讨  

Optimizing management strategies for intravenous iron infusion

作　　者：郭咸希[1] 李义 GUO Xianxi;LI Yi(Department of Pharmacy,Renmin Hospital of Wuhan University,Wuhan 430060,China;Department of Hematology,Renmin Hospital of Wuhan University,Wuhan 430060,China)

机构地区：[1]武汉大学人民医院药学部,武汉430060 [2]武汉大学人民医院血液科,武汉430060

出　　处：《临床药物治疗杂志》2025年第3期19-22,27,共5页Clinical Medication Journal

摘　　要：静脉铁剂已成为治疗缺铁性贫血的重要手段,尤其在口服铁剂疗效不佳或耐受性差及需要快速补铁的缺铁性贫血患者中得到广泛应用。然而,频繁输注导致的患者依从性差、输液反应、铁外渗和药品稀释度等潜在安全问题,限制了静脉铁剂的临床推广。本文重点分析并讨论了这些临床挑战,并基于现有的临床研究、指南推荐和作者的临床经验,提出了相应的应对策略,旨在为优化静脉铁剂输注管理提供参考。Intravenous iron has emerged as a critical treatment for iron deficiency anemia,particularly in patients who exhibit poor response or intolerance to oral iron or require rapid iron replenishment.However,challenges such as poor patient compliance due to frequent infusions,along with safety concerns including infusion reactions,iron extravasation,and improper dilution,hinder its widespread clinical adoption.This review thoroughly examines these clinical issues and proposes practical strategies based on existing clinical research,guideline recommendations,and the authors'clinical experience,aiming to provide valuable insights for optimizing the management of intravenous iron infusion.

关 键 词：静脉铁剂 输注管理 依从性 输液反应 铁外渗 

分 类 号：R973.3[医药卫生—药品] R95[医药卫生—药学]