NLR联合LAD对心房颤动射频消融术后早期复发的预测价值  

The predictive value of NLR combined with LAD for the early recurrence of atrial fibrillation after radiofrequency catheter ablation

作　　者：王晓旭[1] 彭佩云 WANG Xiaoxu;PENG Peiyun(Department of Cardiovascular Medicine,Cardiovascular Research Center,The First Affiliated Hospital of Chongqing Medical University,Chongqing 400016,China)

机构地区：[1]重庆医科大学附属第一医院心血管内科/心血管研究中心,重庆400016

出　　处：《现代医药卫生》2025年第4期853-857,共5页Journal of Modern Medicine & Health

摘　　要：目的探讨中性粒细胞和淋巴细胞计数比值(NLR)及左心房内径(LAD)对心房颤动患者经射频消融术治疗后早期复发的预测价值。方法回顾性收集2022年8月至2024年8月于该院行经导管心脏射频消融术的126例心房颤动患者的临床资料、实验室检查、心脏彩色多普勒超声指标。术后随访3个月,记录患者的复发情况,并将126例患者分为复发组与未复发组。采用logistic回归分析建立预测模型,使用受试者操作特征(ROC)曲线及曲线下面积(AUC)评估上述指标对术后早期复发的预测效率。结果心房颤动复发组36例(28.6%),非复发组90例(71.4%)。复发组患者LAD、B型利钠肽(BNP)、NLR、系统免疫炎症指数(SII)均高于未复发组,差异有统计学意义(P<0.05)。Logistic回归分析显示,NLR、LAD为心房颤动患者术后早期复发的独立预测因素[比值比(OR)>1,P<0.05]。ROC曲线显示,NLR、LAD联合预测早期复发的AUC为0.767,其灵敏度为67%、特异度为81%。结论NLR联合LAD对心房颤动患者射频消融术后早期复发具有一定预测价值。Objective To investigate the predictive value of neutrophil/lymphocyte ratio(NLR)and left atrial diameter(LAD)for atrial fibrillation early recurrence after radiofrequency ablation in atrial fibrillation.Methods From August 2022 to August 2024,126 patients with atrial fibrillation who underwent radiofrequency ablation in the hospital were included.The clinic data,laboratory tests,and echocardiographic data were recorded.Patients were followed up for 3 months after radiofrequency ablation,and the recurrence were recorded.The 126 patients were divided into non-recurrence group and recurrence group.The logistic regression analysis was used to establish the prediction model.Receiver operator characteristic(ROC)curve and area under the curve(AUC)were used to evaluate the prediction efficiency.Results There were 36 patients(28.6%)in the recurrence group,and 90 patients(71.4%)in the non-recurrence group.Compared with the non-recurrent group,LAD,B-type natriuretic peptide(BNP),NLR and systemic immune inflammation index(SII)were significantly higher,the differences were statistically significant(P<0.05).Logistic regression analysis indicated that NLR and LAD were independent risk factors for postoperative early recurrence[odds ratio(OR)>1,P<0.05].The ROC curve showed that the AUC of the combined detection of early recurrence by NLR and LAD was 0.767,with a sensitivity of 67%and a specificity of 81%.Conclusion NLR combined with LAD has a certain predictive value in the evaluation of postoperative early recurrence of atrial fibrillation.

关 键 词：心房颤动 射频消融术 早期复发 中性粒细胞/淋巴细胞值 左心房内径 

分 类 号：R541.7[医药卫生—心血管疾病]