发热待查病因变化趋势及诊治进展  

Progress in change trend of etiology and diagnosis of fever of unknown origin

作　　者：阿迪莱·麦麦提伊敏 张永萍[2] 木尼热·阿地力江 陈星均 Adilai Maimaitiyimin;ZHANG Yongping;Munire Adilijiang;CHEN Xingjun(Graduate School of Xinjiang Medical University,Urumqi,Xinjiang 830011,China;Department of Infectious Diseases,People′s Hospital of Xinjiang Uygur Autonomous,Urumqi,Xinjiang 830001,China)

机构地区：[1]新疆医科大学研究生学院,新疆乌鲁木齐830011 [2]新疆维吾尔自治区人民医院感染性疾病科,新疆乌鲁木齐830001

出　　处：《现代医药卫生》2025年第4期1006-1009,1014,共5页Journal of Modern Medicine & Health

基　　金：新疆维吾尔自治区自然科学基金项目(2022D01C115)。

摘　　要：发热待查(FUO)定义为发热体温大于38.3℃,发热持续时间超过3周,并于医院内诊治1周后仍未明确诊断的患者。随着医疗水平的发展,定义也得到不断完善。目前报道的FUO病因超过200种,病因复杂,临床诊断困难,诊断需依靠详细的临床病史收集、体格检查、实验室指标、影像资料等综合找出相关线索。FUO的病因在不同时间段及不同国家的分布因健康状况和社会经济条件而异。目前,没有具体的治疗方案,而经验性治疗存在争议。病因学分类的研究可以为临床工作者提供有效的线索,该文主要探讨目前FUO患者病因的分布及病原构成变化趋势。Fever of unknown origin(FUO)is defined as patients with a fever whose body temperature is greater than 38.3℃,whose fever lasts for more than 3 weeks,and whose diagnosis is not clear after one week of hospital treatment.With the development of medical standards,the definition has been improved.At present,there are more than 200 reported causes of FUO to be investigated,which are complicated and difficult to diagnose clinically.The diagnosis needs to be based on detailed clinical history collection,physical examination,laboratory and imaging data to find out relevant clues.The causes of fever under investigation FUO varies over time and across countries,depending on health status and socio-economic conditions.At present,there is no clear treatment method,and empirical treatment is still controversial.The study of etiology classification can provide effective clues for clinical workers.This paper mainly discussed the changing trend of the distribution of etiology and pathogen composition in FUO patients.

关 键 词：发热待查 病因 变化趋势 综述 

分 类 号：R597[医药卫生—内科学]