Intelligent hydrogel-based dressings for treatment of chronic diabetic wounds  

作　　者：Huan Liu Li He 

机构地区：[1]School of Chemistry and Chemical Engineering,Beijing Institute of Technology,Beijing 100000,China

出　　处：《World Journal of Diabetes》2025年第5期71-88,共18页世界糖尿病杂志(英文)

摘　　要：Diabetic wounds represent a significant challenge in the medical field,significantly impacting patient quality of life and imposing a heavy burden on healthcare systems.Intelligent hydrogel dressings have attracted significant attention in diabetic wound treatment due to their unique properties.This review systematically explores the three main categories of intelligent hydrogels(natural,synthetic,and composite),dissecting their composition,structure,and the mechanisms that enable their intelligent responses.The crucial roles of these dressings in maintaining a moist wound environment,efficiently absorbing exudate,and precisely delivering drugs are expounded.Moreover,their application advantages in combating bacteria and infections,regulating inflammation and immunity,promoting angiogenesis and tissue regeneration,as well as enabling real-time monitoring and personalized treatment,are explored in depth.Additionally,we discuss future research directions and the prospects for personalized precision medicine in diabetic wound care,aiming to inspire innovation and provide a comprehensive theoretical basis for the development of nextgeneration intelligent dressings.

关 键 词：Intelligent dressings Diabetic wounds HYDROGEL Stimuli-responsive polymers Drug delivery systems 

分 类 号：R318.08[医药卫生—生物医学工程]