Using vaporized hydrogen peroxide for anhydrous disinfection of gastrointestinal endoscopes  

作　　者：Can Zhao Li-Hong Qi Long-Song Li Ying-Ying Wang Ting Liang Ning-Li Chai 

机构地区：[1]Chinese PLA Medical School,Beijing 100853,China [2]Department of Gastroenterology,The First Medical Center of Chinese PLA General Hospital,Beijing 100853,China [3]Institute of NBC Defence PLA Army,Beijing 102205,China

出　　处：《World Journal of Gastroenterology》2025年第14期106-117,共12页世界胃肠病学杂志(英文)

基　　金：Supported by the Joint Logistics Support Force Comprehensive Equipment Research Project,No.LB2023B010100-09.

摘　　要：BACKGROUND Current disinfection methods for gastrointestinal endoscopes consume a significant amount of water resources and produce a large volume of waste.AIM To achieve the objectives of efficiency,speed,and cost-effectiveness,this study utilized vaporized hydrogen peroxide(VHP)generated from sodium percarbonate granules to conduct an anhydrous disinfection test on gastrointestinal endoscopes.METHODS The experimental device rapidly converts sodium percarbonate granules into VHP,and performs disinfection experiments on gastrointestinal endoscope models,disposable endoscopes,and various types of reusable gastrointestinal endoscopes.Variables such as the intraluminal flow rate(FR),relative humidity(RH),exposure dosage,and organic burden are used to explore the factors influencing the disinfection of long and narrow lumens with VHP.RESULTS The device generates a certain concentration of VHP that can achieve high-level disinfection of endoscope models within 30 minutes.RH,exposure dosage,and organic burden significantly affect the disinfection efficacy of VHP,whereas the intraluminal FR does not significantly impact disinfection efficacy.All ten artificially contaminated disposable endoscopes achieved satisfactory disinfection results.Furthermore,when this device was used to treat various types of reusable endoscopes,the disinfection and sterilization effects were not significantly different from those of automatic endoscope disinfection machines(using peracetic acid disinfectant solution)(P>0.05),and the economic cost of disinfectant required per endoscope was lower(1.5 China Yuan),with a shorter disinfection time(30 minutes).CONCLUSION The methods and results of this study provide a basis for further research on the use of VHP for the disinfection of gastrointestinal endoscopes,as well as for the development of anhydrous disinfection technology for gastrointestinal endoscopes.

关 键 词：Gastrointestinal endoscope Vaporized hydrogen peroxide Sodium percarbonate granules Bacillus subtilis Anhydrous disinfection 

分 类 号：R187[医药卫生—流行病学]