骶四针电针联合翁沥通胶囊治疗湿热瘀滞型慢性前列腺炎/慢性盆腔疼痛综合征的疗效观察  

Efficacy observation of Di Si Zhen electroacupuncture combined with Weng Li Tong capsules in treating chronic prostatitis/chronic pelvic pain syndrome of damp heat stagnation type

作　　者：周舒宁 陈柏鸿 王国平 ZHOU Shuning;CHEN Baihong;WANG Guoping(The Ninth People's Hospital of Hangzhou,Hangzhou 311225,China)

机构地区：[1]浙江省杭州市第九人民医院,杭州311225

出　　处：《上海针灸杂志》2025年第4期464-470,共7页Shanghai Journal of Acupuncture and Moxibustion

基　　金：浙江省自然科学基金探索项目(LQ23H270018);杭州市卫生计生科技计划一般项目(A20220432)。

摘　　要：目的 观察骶四针电针联合翁沥通胶囊治疗湿热瘀滞型慢性前列腺炎/慢性盆腔疼痛综合征的临床疗效及安全性。方法 将66例湿热瘀滞型慢性前列腺炎/慢性盆腔疼痛综合征患者随机分为对照组和观察组,每组33例。对照组予口服翁沥通胶囊治疗,观察组在对照组口服翁沥通胶囊基础上联合骶四针电针治疗。观察两组治疗前、治疗后、随访1个月和随访3个月美国国立卫生研究院慢性前列腺炎症状指数(National Institutes of Health chronic prostate inflammation symptoms index, NIH-CPSI)、中医证候积分、医院焦虑与抑郁量表(hospital anxiety and depression scale, HADS)评分的变化,比较两组临床疗效和不良反应发生情况。结果 观察组总有效率为97.0%,优于对照组的72.7%,差异具有统计学意义(P<0.05)。两组治疗后、随访1个月和随访3个月NIH-CPSI各单项评分和总分、中医证候积分和HADS评分均优于同组治疗前(P<0.05),两组随访1个月和随访3个月NIH-CPSI各单项评分和总分、中医证候积分和HADS评分均优于同组治疗后(P<0.05),两组随访3个月NIH-CPSI各单项评分和总分、中医证候积分和HADS评分均优于同组随访1个月(P<0.05)。观察组治疗后和随访1个月NIH-CPSI各单项评分和总分、中医证候积分和HADS评分均优于对照组(P<0.05);NIH-CPSI各单项评分和总分组别和时间存在交互作用,差异具有统计学意义(P<0.05)。两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论 骶四针电针联合口服翁沥通胶囊治疗湿热瘀滞型慢性前列腺炎/慢性盆腔疼痛综合征的临床疗效优于单一口服翁沥通胶囊,能更有效地改善临床症状,缓解患者焦虑和抑郁情绪,且安全性较好。Objective To observe the clinical efficacy and safety of Di Si Zhen(four specific points in the sacral region)electroacupuncture combined with Weng Li Tong capsules in treating chronic prostatitis/chronic pelvic pain syndrome(CP/CPPS)of damp heat stagnation type.Method Sixty-six patients with CP/CPPS of damp heat stagnation type were randomly divided into a control group and an observation group,with 33 cases in each group.The control group received oral Weng Li Tong capsules,while the observation group received Di Si Zhen electroacupuncture on the basis of oral Weng Li Tong capsules.The changes in the National Institutes of Health chronic prostatitis symptom index(NIH-CPSI)scores,traditional Chinese medicine(TCM)syndrome scores and hospital anxiety and depression scale(HADS)scores of both groups were observed before treatment,after treatment,at 1-month and 3-month follow-ups.The clinical efficacy and adverse reactions were compared between the two groups.Result The total effective rate in the observation group was 97.0%,significantly higher than 72.7%in the control group(P<0.05).The individual item scores and total scores of NIH-CPSI,TCM syndrome scores and HADS scores after treatment,1-month and 3-month follow-ups were better than those before treatment in both groups(P<0.05),and the individual item scores and total scores of NIH-CPSI,TCM syndrome scores and HADS scores after 1-month and 3-month follow-ups were better than those after treatment in the two groups(P<0.05).The individual item scores and total scores of NIH-CPSI,TCM syndrome scores and HADS scores of the two groups at 3-month follow-up were better than those at 1-month follow-up(P<0.05).After treatment and 1-month follow-up,the single item scores and total scores of NIH-CPSI,TCM syndrome scores and HADS scores in the observation group were better than those in the control group(P<0.05).There was an interaction between group and time for single item score and total score of NIH-CPSI,and the difference was statistically significant(P<0.05).There was

关 键 词：针刺疗法 电针 针药并用 前列腺炎 腹痛 湿热瘀滞 

分 类 号：R246.2[医药卫生—针灸推拿学]