广西野生猕猴肝炎病毒血清流行病学调查  

Seroepidemiological investigation of hepatitis viruses in wild macaques in Guangxi

作　　者：侯江宁 张陆娟[2] 曾奇 胡莉萍[2] 隆丽梅 许宾达 陈钦艳[2] Hou Jiangning;Zhang Lujuan;Zeng Qi;Hu Liping;Long Limei;Xu Binda;Chen Qinyan(Nanning Wild Animals and Plants Protection Station,Guangxi Nanning 530021;Guangxi Center for Disease Control and Prevention,Guangxi Key Laboratory for the Prevention and Control of Viral Hepatitis,Guangxi Nanning 530028;Guangxi Mount Longhu Nature Reserve Management Office,Guangxi Nanning 532700)

机构地区：[1]南宁市野生动植物保护站,广西南宁530021 [2]广西壮族自治区疾病预防控制中心,广西病毒性肝炎防治研究重点实验室,广西南宁530028 [3]广西龙虎山自然保护区管理处,广西南宁532700

出　　处：《现代畜牧兽医》2025年第3期63-65,共3页Modern Journal of Animal Husbandry and Veterinary Medicine

基　　金：国家自然科学基金项目(81703283);广西壮族自治区疾病预防控制中心青年科技工作者科研课题项(202402)。

摘　　要：研究旨在了解广西野生猕猴甲型肝炎病毒(HAV)、乙型肝炎病毒(HBV)、丙型肝炎病毒(HCV)和戊型肝炎病毒(HEV)感染情况。采用酶联免疫吸附试验(ELISA)对广西某自然保护区67只野生猕猴血清样本进行HAV-免疫球蛋白M(IgM)抗体、HEV-IgM抗体、HCV抗体和HBV表面抗原(HBsAg)检测,采用PCR荧光探针法检测血清样本HAV、HBV、HCV和HEV核酸。结果显示,HBsAg及HCV抗体均为阴性,HAVIgM抗体、HEV-IgM抗体阳性率分别为1.49%(1/67)、4.48%(3/67);未检出HAV、HBV、HCV核酸,HEV核酸阳性率为1.49%(1/67)。研究表明,广西野生猕猴可感染或携带HAV、HEV,未检出HBV、HCV阳性个体。This study aimed to investigate the prevalence of hepatitis A virus(HAV),hepatitis B virus(HBV),hepatitis C virus(HCV),and hepatitis E virus(HEV)infections in wild macaques in Guangxi.Serum samples from 67 wild macaques in a Guangxi nature reserve were tested for HAV-immunoglobulin M(IgM)antibodies,HEV-IgM antibodies,HCV antibodies,and HBV surface antigen(HBsAg)using enzyme-linked immunosorbent assay(ELISA).Nucleic acids of HAV,HBV,HCV,and HEV were detected using PCR fluorescent probe assays.Results showed that HBsAg and HCV antibodies were all negative.The positive rates for HAV-IgM and HEV-IgM antibodies were 1.49%(1/67)and 4.48%(3/67),respectively.No HAV,HBV,or HCV nucleic acids were detected,while HEV nucleic acid positivity was 1.49%(1/67).The study indicates that wild macaques in Guangxi can be infected with or carry HAV and HEV,but no HBV or HCV positive individuals were detected.

关 键 词：野生猕猴 肝炎病毒 血清流行病学 

分 类 号：S855.3[农业科学—临床兽医学]