某规模化猪场伪狂犬病的净化及经济效益分析  

Elimination and economic benefit analysis of pseudorabies in a large-scale pig farm

作　　者：徐岳涛 李孝文 李洋 吴伟胜 于冲 田梦婷 白娟[1] 姜平 XU Yuetao;LI Xiaowen;LI Yang;WU Weisheng;YU Chong;TIAN Mengting;BAI Juan;JIANG Ping(College of Veterinary Medicine,Nanjing Agricultural University,Nanjing 210095,China;Shandong Engineering Research Center of Pig and Poultry Health Breeding and Important Disease Purification/Shandong New Hope Liuhe Co.,Ltd.,Qingdao 266100,China)

机构地区：[1]南京农业大学动物医学院,江苏南京210095 [2]猪禽健康养殖与重要疫病净化山东省工程研究中心/山东新希望六和集团有限公司,山东青岛266100

出　　处：《畜牧与兽医》2025年第5期107-113,共7页Animal Husbandry & Veterinary Medicine

基　　金：江苏省农业科技自主创新资金项目(CX(23)3073);国家生猪产业技术体系专项(CARS-35)。

摘　　要：为了探究规模化猪场伪狂犬病净化的可行性,选择某大型父母代养猪场,通过“检测-隔离/淘汰-免疫”手段净化猪伪狂犬病。采集所有公猪、经产母猪、后备母猪,以及部分仔猪和保育猪的血清样品,根据抗体检测结果,对PRV-gE抗体阴性猪进行隔离饲养,淘汰PRV-gE抗体阳性猪及其同栏猪只;针对不同猪群调整免疫方案,增加产前母猪、初生仔猪和保育猪的免疫次数,解决免疫空窗期问题。加强后备猪监测,严格实行“全进全出”,及时隔离病猪,加大淘汰力度,加强人员、物品和环境消毒;严格执行上述净化措施,每6个月进行PRV抗体检测。结果显示:随着净化工作的开展,gB抗体阳性率逐渐升高,gE抗体阳性率逐渐降低;持续采取净化措施2年后,经产母猪和后备母猪群体的gB抗体阳性率均达到97%以上,且各阶段猪只gE抗体均为阴性,表明该猪场已达到伪狂犬病净化标准;经统计分析,伪狂犬病净化后,该场每头母猪每年断奶仔猪数(PSY)平均增加4.96头,每头母猪每年收益平均增加1 636元。结论:通过科学的净化技术方案和严格的生物安全措施,可以实现规模化猪场的伪狂犬病净化,提高猪场经济效益。This study was to explore elimination of pseudorabies(PR) through the “detection-isolation/elimination-immunization” approach in a large-scale parent-raising pig farm.Serum samples were collected from all boars,sows,and gilts,as well as a proportion of suckling piglets and nursery pigs.According to the results of the antibody detection,pigs with negative PRV-gE antibodies were isolated,while PRV-gE antibody-positive pigs and close contacts were eliminated.The immunization schedules were optimized for different pig groups with the objective of strengthening the vaccination of prenatal sows,newborn piglets,and nursery pigs.Furthermore,a series of measures were implemented to enhance the management of replacement pigs,including the strict implementation of the “all in,all out” principle,the timely elimination of sick pigs,and the enhanced disinfection of personnel,materials,and the environment.In accordance with the aforementioned measures,PRV antibody testing was conducted every six months.The results showed a gradual increase in gB antibody seroconversion and a gradual decrease in gE antibody seroconversion as a result of the elimination process.Two years later,the gB antibody positivity rate of both the sows and gilts reached over 97%,while no further gE-positive pigs were detected in all pig herds,indicating that the farm had met the PR elimination standard.The statistical analysis revealed that,following the PR elimination,the PSY of the farm increased by 4.96,and the average annual income per sow increased by 1 636 yuan.This case study illustrated that the elimination of PR in large-scale pig farms could be achieved through the application of scientific elimination techniques and strict biosafety measures,which would improve the econom-ic income of pig farms.

关 键 词：伪狂犬病 净化 gE抗体 gB抗体 经济效益 

分 类 号：S855[农业科学—临床兽医学]