家禽胚胎干细胞研究进展及其应用  

Recent advances in avian embryonic stem cell research and applications

作　　者：李鑫璐 李浩杰 谭磊 张勇 王坤[1] 葛长荣[1] LI Xinlu;LI Haojie;TAN Lei;ZHANG Yong;WANG Kun;GE Changrong(College of Animal Science and Technology,Yunnan Agricultural University,Kunming 650201,China)

机构地区：[1]云南农业大学动物科学技术学院,云南昆明650201

出　　处：《畜牧与兽医》2025年第5期140-146,共7页Animal Husbandry & Veterinary Medicine

基　　金：云南联合基金项目(U2002205)。

摘　　要：家禽胚胎干细胞(ESCs)作为具有高度多能性的细胞,在家禽遗传育种和生物医学研究中展现出重要价值。本文综述了家禽ESCs的概念、特点、维持和分化机制,以及它们在疫苗生产、生物反应器、遗传育种和人类医学研究中的应用。随着分子生物学技术的不断进步,家禽ESCs的研究进一步揭示了胚胎干细胞的分化机制,也为未来的生物技术应用提供了新的方向。Avian embryonic stem cells(ESCs),characterized by their high pluripotency,play a significant role in poultry genetic breeding and biomedical research.This review summarized the fundamental concepts,key characteristics,maintenance mechanisms,and differentiation pathways of avain ESCs.Furthermore,this paper explored the potential applications of ESCs in vaccine production,bioreactor technology,genetic breeding,and human medical research.With the continuous advancement of molecular biology techniques,the study of avian ESCs had further revealed the differentiation mechanisms of embryonic stem cells,and provided a new direction for future biotechnology applications.

关 键 词：胚胎干细胞 分化 信号通路 

分 类 号：S831[农业科学—畜牧学]