儿童感染后继发性机化性肺炎的诊断与治疗  

Diagnosis and treatment of secondary organizing pneumonia in children after infection

作　　者：桑梦鸿 张淑艳 张素琴[1] SANG Menghong;ZHANG Shuyan;ZHANG Suqin(Department of Pediatrics Respiratory,The First Affiliated Hospital of Zhengzhou University,Zhengzhou 450000,China)

机构地区：[1]郑州大学第一附属医院儿童呼吸内科,河南郑州450000

出　　处：《山东医药》2025年第4期10-15,共6页Shandong Medical Journal

摘　　要：目的总结儿童感染后继发性机化性肺炎(SOP)的诊断与治疗方法。方法回顾性分析1例儿童感染后SOP的临床资料,另通过文献检索回顾国内外报道的儿童SOP相关病例。结果该例患儿以持续干咳为主要临床表现,胸部CT检查及支气管镜肺活检结果符合SOP,诊断为感染后SOP;给予抗感染和激素治疗后,CT检查病变明显吸收。通过文献检索发现共报道11例SOP患儿,病因多样,影像表现复杂不一,多数病例经糖皮质激素治疗效果良好,生存率较高。结论儿童感染后SOP诊断需结合临床表现、影像学检查、支气管镜肺活检及病理四个方面,其中病理检查为金标准;尽早确诊并给予抗感染、激素治疗,预后良好。Objective To summarize the clinical diagnosis and treatment of secondary organizing pneumonia(SOP)in children after infection.Methods We retrospectively analyzed the clinical data of a child with SOP after infection,and reviewed the reported cases of pediatric SOP through literature search.Results The patient presented with persis-tent dry cough as the main clinical symptom.The chest CT imaging and bronchoscopy biopsy results were consistent with SOP,and the diagnosis was post-infectious SOP;the CT lesions were significantly absorbed with anti-infection and steroid therapy.Eleven cases of SOP children with a variety of etiology and intricate and varied imaging presentations were docu-mented after a survey of the literature.The majority of cases had a high survival rate and responded favorably to glucocorti-coid therapy.Conclusions The diagnosis of SOP in children after infection requires the integration of clinical manifesta-tions,imaging,bronchoscopy biopsy,and pathology,with pathology being the gold standard.Early diagnosis and the ad-ministration of anti-infection and hormone therapy lead to a good prognosis.

关 键 词：机化性肺炎 继发性机化性肺炎 感染 儿童 病理检查 激素 

分 类 号：R725.6[医药卫生—儿科]