心血管健康评价指标对不孕症患者IVF/ICSI助孕结局影响的研究进展  

Research progress on impact of cardiovascular health indicators on IVF/ICSI outcomes in infertile patients

作　　者：张文 肖铭芳 韩新美 陈新霞[3] ZHANG Wen;XIAO Mingfang;HAN Xinmei;CHEN Xinxia(Center for IVF-ET,Institute of Women,Children and Reproductive Health of Shandong University/Hospital for Reproductive Medicine Affiliated to Shandong University,Jinan 250001,China;不详)

机构地区：[1]山东大学妇儿与生殖健康研究院/山东大学附属生殖医院IVF-ET室,山东济南250001 [2]山东大学妇儿与生殖健康研究院/山东大学附属生殖医院医院办公室,山东济南250001 [3]山东大学护理与康复学院,山东济南250100

出　　处：《山东医药》2025年第4期155-159,共5页Shandong Medical Journal

基　　金：山东省自然科学基金面上项目(ZR2020MH064);山东省社会科学规划研究项目(24CSHJ05)。

摘　　要：不孕症是育龄夫妇常见的生殖健康问题,辅助生殖技术是其重要的治疗手段。体外受精(IVF)/卵胞质内单精子显微注射(ICSI)是辅助生殖技术中的主要方法,广泛应用于不孕症的治疗,但其成功率及妊娠并发症发生率仍有待改善。身体质量指数、血压、血糖和血脂等心血管健康评价指标是较易获得且通过干预可改变的参数,其不仅可用于量化心血管健康,还被发现与不孕症女性接受IVF/ICSI助孕后的早期胚胎发育、妊娠过程、妊娠并发症以及分娩结局存在关联。探讨单个或多个心血管健康评价指标对不孕症患者IVF/ICSI助孕结局的影响,可为临床优化不孕症患者的助孕策略提供帮助。Infertility is a common reproductive health issue among couples of reproductive age,and assisted reproduc-tive technology(ART)serves as a critical therapeutic approach.In vitro fertilization(IVF)/intracytoplasmic sperm injec-tion(ICSI),the primary ART methods widely utilized in infertility treatment,still require improvement in success rates and reduction of pregnancy-related complications.Cardiovascular health indicators,including body mass index(BMI),blood pressure,blood glucose,and lipid profiles,are readily accessible and modifiable parameters through interventions.These indicators not only quantify cardiovascular health but are closely associated with early embryonic development,preg-nancy progression,pregnancy complications,and delivery outcomes in infertile women undergoing IVF/ICSI.Investigat-ing the impact of individual or combined cardiovascular health indicators on IVF/ICSI outcomes in infertile patients may provide valuable insights for optimizing clinical strategies in assisted reproduction.

关 键 词：不孕症 辅助生殖技术 体外受精 卵胞质内单精子显微注射 心血管健康 

分 类 号：R473.71[医药卫生—护理学]