肾移植受者结核潜伏感染预防治疗研究进展  

Research progress on the prevention and treatment of latent tuberculosis infection in renal transplant recipients

作　　者：潘建勇 付迎欣 Pan Jianyong;Fu Yingxin(First Department of Kidney Transplant,Organ Transplant Institute,Shenzhen Third People's Hospital,the Second Affiliated Hospital,Southern University of Science and Technology,National Clinical Research Center for Infectious Disease,Shenzhen 518100,China)

机构地区：[1]深圳市第三人民医院,南方科技大学第二附属医院,国家感染性疾病临床研究中心,器官移植研究所,肾移植一科,深圳518100

出　　处：《中华器官移植杂志》2025年第3期239-243,共5页Chinese Journal of Organ Transplantation

基　　金：深圳市高水平医院建设专项(XJ2022019601,24250G1036)。

摘　　要：结核病是危害全球公共卫生安全的高致死感染性疾病之一。肾移植受者结核潜伏感染(latent tuberculosis infection,LTBI)发生率高于普通人群并影响移植预后,早期筛查及预防治疗可有效减少LTBI再激活。本文综述了近年来肾移植受者LTBI的流行病学特征、筛查诊断方法及预防策略等方面的最新进展,为肾移植受者LTBI的防控提供参考和启示。Tuberculosis remains one of the most lethal infectious diseases,posing a significant threat to global public health.Kidney transplant recipients have a higher incidence of latent tuberculosis infection(LTBI)than the general population,which adversely affects transplant outcomes.Early screening and prophylactic treatment are essential in reducing the risk of LTBI reactivation.This review summarizes recent advances in the epidemiology,screening and diagnostic methods,and preventive strategies for LTBI in kidney transplant recipients,providing valuable insights and references for its prevention and management in this high-risk population.

关 键 词：肾移植 结核潜伏感染 流行病学 诊断筛查 预防治疗 

分 类 号：R699.2[医药卫生—泌尿科学]