基于药物利用研究指标评价质子泵抑制剂的DRGs费用及合理性  

Evaluation of DRGs Cost and Rationality of Proton Pump Inhibitors Based on the Drug Utilization Research Indexes

作　　者：寸玉芳 陈然坤 雀苏云 杨盛菊 苏艳梅 邱成省 CUN Yufang;CHEN Rankun;QUE Suyun;YANG Shengju;SU Yanmei;QIU Chengxing(Dali Bai Autonomous Prefecture People's Hospital,Dali,Yunnan,China 671000)

机构地区：[1]云南省大理白族自治州人民医院,云南大理671000

出　　处：《中国药业》2025年第9期16-19,共4页China Pharmaceuticals

基　　金：云南省教育厅科学研究基金项目[2022J0745]。

摘　　要：目的基于药物利用研究(DUR)指标评价质子泵抑制剂(PPIs)的疾病诊断相关分组(DRGs)费用及合理性,为医疗机构合理用药提供参考。方法根据6个DRGs分组(第一组至第六组)收集云南省大理白族自治州某三级综合医院2022年1月至6月(干预前)和2022年7月至12月(干预后)收治的消化系统疾病患者使用PPIs的药品费用等相关信息,并对各组的DUR指标[包括用药频度(DDDs)、药物利用指数(DUI)、PPIs使用率、使用强度(AUD)]及医嘱的合理性进行评价。结果干预后,第三组、第四组、第六组的PPIs平均用药金额较干预前下降,第一组、第二组、第五组的PPIs平均用药金额较干预前上升;在平均药占比方面,干预后,第四组和第六组的平均药占比较干预前下降,第一组、第二组、第三组、第五组的平均药占比较干预前上升。干预后,第四组和第六组的DUI较干预前减少,第一组、第二组、第三组、第五组较干预前增加。第三组的PPIs使用率从90.32%下降至64.29%。干预前后,第一组、第二组、第五组PPIs的AUD均高于第三组、第四组、第六组。各组干预后的处方合格率均较干预前上升,分别为80.00%,53.33%,92.86%,84.62%,78.79%,53.62%。结论基于DUR指标评价PPIs的DRGs费用及用药合理性具有科学性和可行性。Objective To evaluate the cost and rationality of diagnosis-related group(DRGs)for proton pump inhibitors(PPIs)based on drug utilization research(DUR)indexes,and to provide a reference for rational drug use in medical institutions.Methods Based on six DRGs groups(groupsⅠ-Ⅵ),relevant information on the drug costs of PPIs used by patients with digestive system diseases admitted to a tertiary general hospital in Dali Bai Autonomous Prefecture,Yunnan Province from January to June 2022(before intervention)and from July to December 2022(after intervention)was collected.The DUR indexes[including defined daily dose system(DDDs),drug utilization index(DUI),PPIs usage rate,and antibiotics use density(AUD)]and the rationality of medical orders in each group were evaluated.Results Compared to those before intervention,the average medication cost of PPIs in the groupsⅢ,Ⅳ,Ⅵdecreased after intervention,while that in the groupsⅠ,Ⅱ,Ⅴgroups increased after intervention.In terms of average drug proportion,compared to those before intervention,the average drug proportion in groupsⅣ,Ⅵdecreased after intervention,while that in groupsⅠ,Ⅱ,Ⅲ,Ⅴincreased after intervention.Compared to those before intervention,the DUI in groupsⅣ,Ⅵdecreased after intervention,while that in groupsⅠ,Ⅱ,Ⅲ,Ⅴincreased after intervention.The usage rate of PPIs in groupⅢdecreased from 90.32%to 64.29%.Before and after intervention,the AUD of PPIs in groupsⅠ,Ⅱ,Ⅴwas higher than that in groupsⅢ,Ⅳ,Ⅵ.Compared with those before intervention,the prescription qualification rates in groupsⅠ-Ⅵafter intervention were higher(80.00%,53.33%,92.86%,84.62%,78.79%,and 53.62%,respectively).Conclusion Evaluating the DRGs cost and medication rationality of PPIs based on DUR indexes is scientific and feasible.

关 键 词：质子泵抑制剂 疾病诊断相关分组 药品费用 药物利用研究指标 合理用药 

分 类 号：R95[医药卫生—药学] R975.2