脑血康滴丸联合疏肝解郁胶囊治疗气滞血瘀型中风后抑郁临床观察  

Naoxuekang Dropping Pills Combined with Shugan Jieyu Capsules in the Treatment of Post-stroke Depression of Stagnation of Qi and Blood Stasis Type

作　　者：张义军 ZHANG Yijun(Department of Traditional Chinese Medicine,Jinzhan Second Community Health Service Center of Chaoyang District,Beijing 100018,)

机构地区：[1]北京市朝阳区金盏第二社区卫生服务中心中医科,北京100018

出　　处：《中国中医药现代远程教育》2025年第6期129-132,共4页Chinese Medicine Modern Distance Education of China

摘　　要：目的研究脑血康滴丸联合疏肝解郁胶囊治疗气滞血瘀型中风后抑郁(PSD)的临床效果及安全性。方法以80例气滞血瘀型PSD患者为研究对象,以随机数字表法分为对照组与治疗组,各40例。两组患者均接受常规治疗,对照组给予疏肝解郁胶囊,治疗组在此基础之上联合脑血康滴丸,治疗8周。治疗前后分别采用汉密尔顿抑郁量表(HAMD)、Barthel指数(BI)评定量表、美国国立卫生研究院卒中量表(NIHSS)、蒙特利尔认知功能评估量表(MoCA)评估临床疗效并记录不良反应。结果与对照组相比,治疗组HAMD、NIHSS评分显著降低,BI、MoCA评分显著升高,差异均有统计学意义(P<0.05)。两组不良反应发生情况差异无统计学意义(P>0.05)。结论相较于单独使用疏肝解郁胶囊,联合脑血康滴丸疗效更确切、抗抑郁效果更好,且不良反应发生率低。Objective To investigate the clinical effect and safety of Naoxuekang dropping pills combined with Shugan Jieyu Capsules in the Treatment of post-stroke depression(PSD)of stagnation of qi and blood stasis type.Methods Eighty patients with PSD of stagnation of qi and blood stasis type were divided into control group and treatment group by random number table method,with 40 cases in each group.Patients in both groups received conventional treatment,the control group was given Shugan Jieyu capsule,and the treatment group was treated with Naoxuekang dropping pill on the basis of the control group for 8 weeks.Hamilton Depression Scale(HAMD),Barthel Index(BI)rating scale,National Institutes of Health Stroke Scale(NIHSS)and Montreal Cognitive Function Assessment Scale(MoCA)were used before and after treatment to evaluate clinical efficacy and record adverse reactions.Results Compared with the control group,HAMD and NIHSS scores in the treatment group were significantly decreased,BI and MoCA scores were significantly increased,and the difference was statistical significance(P<0.05).There was no significant difference in the occurrence of adverse reactions between the two groups(P>0.05).Conclusion Compared with Shugan Jieyu capsule,the effect of using Shugan Jieyu capsule combined with Shugan Jieyu capsules in the treatment of PSD is more accurate,and has better antidepressant effect and lower incidence of adverse reactions.

关 键 词：郁证 中风后抑郁 气滞血瘀证 脑血康滴丸 疏肝解郁胶囊 中医药疗法 

分 类 号：R277.7[医药卫生—中医学]