机构地区:[1]河南中医药大学第一附属医院儿科医院,郑州450000 [2]河南中医药大学儿科医学院,郑州450046 [3]河南中医药大学中医学院,郑州450046 [4]中国中医科学院西苑医院,北京100091
出 处:《中国实验方剂学杂志》2025年第9期219-227,共9页Chinese Journal of Experimental Traditional Medical Formulae
基 金:国家自然科学基金项目(81973904);河南省特色骨干学科中医学学科建设项目(STG-ZYX06-202144)。
摘 要:升降散是临床常用、疗效确切的一首温病经典名方,笔者发现该方出处众说纷纭,且尚无学者考证关键信息。该文采用文献计量法对升降散的出处、组成等关键信息进行全面考证。经考证,升降散总共有“内府仙方”“加味僵黄丸”“赔赈散”“太极丸”4个同方异名,升降散首以“内府仙方”为名见于明代龚廷贤所著《万病回春》,经清代杨栗山传承和发扬广为流传至今。剂型分为丸剂和散剂2种,当代以散剂流行。据明清度量衡剂量换算建议该方入丸剂则单次制备需僵蚕74.6 g,姜黄、蝉蜕各9.325 g,大黄149.2 g,单次服用剂量为僵蚕1.15 g,姜黄、蝉蜕各0.14 g,大黄2.3 g,小儿用量减半。散剂病情轻者单次剂量为僵蚕1.84 g、蝉蜕0.92 g、姜黄0.28 g、大黄3.68 g;病情重者单次剂量为僵蚕2.48 g、蝉蜕1.23 g、姜黄0.37 g、大黄4.91 g,病情最重者僵蚕3.68 g、蝉蜕1.84 g、姜黄0.55 g、大黄7.36 g。4味药物研成均匀细末,病轻者,分4次服,每服6.71 g,用黄酒200 mL,蜂蜜18.65 g,搅拌均匀冷服,症状好转即可停药。病重者,分3次服,每服8.95 g,黄酒300 mL,蜂蜜27.98 g,搅拌均匀冷服。最重者,分2次服,每服13.43 g,黄酒400 mL,蜂蜜37.3 g,搅拌均匀冷服。全方升清降浊,散风清热,主治温病表里三焦大热,现代临床运用广泛。该研究厘清升降散流传脉络,考证其关键信息表,为学者研究提供参考并为其推向市场转化提供理论依据。Shengjiangsan is a classic formula for treating warm diseases with wide clinical application and accurate efficacy.There are different opinions on the origin of this formula and lacks key information research on this formula.Therefore,in this study,we conducted systematic research into the historic origin,composition,and other key information of this Shengjiangsan.Results showed that Shengjiangsan has different versions,with"Neixian Fufang","Jiawei Jianghuangwan","Peizhensan",and"Taijiwan"being the same formula with different names.Shengjiangsan was first recorded as"Neixian Fufang"in Wanbing Huichun written by GONG Tingxian from the Ming dynasty,inherited and developed by YANG Lishan from Qing dynasty,and has been passed down to modern times.Pills and powder are two main forms of Shengjiangsan,and powder has become more popular nowadays.According to the measurement system of Ming and Qing dynasties,the recommended dosage and usage of Shengjiangsan are as follows.For the pill version of Shengjiangsan,Bombyx Batryticatus of 74.6 g,Curcumae Longae Rhizoma of 9.325 g,Cicadae Periostracum of 9.325 g,and Rhei Radix et Rhizoma of 149.2 g were processed into pills for preparation.Single dosage is Bombyx Batryticatus of 1.15 g,Curcumae Longae Rhizoma of 0.14 g,Cicadae Periostracum of 0.14 g,and Rhei Radix et Rhizoma of 2.3 g,with halved dosage applied for children.For the powder version of Shengjiangsan,the dosage varied in accordance with the severity of the disease.Bombyx Batryticatus of 1.84 g,Curcumae Longae Rhizoma of 0.28 g,Cicadae Periostracum of 0.92 g,and Rhei Radix et Rhizoma of 3.68 g were processed into powder for patients with mild symptoms.Bombyx Batryticatus of 2.48 g,Curcumae Longae Rhizoma of 0.37 g,Cicadae Periostracum of 1.23 g,and Rhei Radix et Rhizoma of 4.91 g were processed into powder for patients with severe symptoms.Bombyx Batryticatus of 3.68 g,Curcumae Longae Rhizoma of 1.84 g,Cicadae Periostracum of 0.55 g,and Rhei Radix et Rhizoma of 7.36 g were processed into powder for patients with critic
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