慢性前列腺炎伴精索静脉曲张患者高位结扎术对慢性前列腺炎症状及血清睾酮的影响  

Effect of high ligation of spermatic vein on leukocytes in expressed prostate secretion of patients with chronic prostatitis and varicocele

作　　者：丁吉阳 张鹏 牛春华 李海勇 徐文柱 张英晨 马刚 DING Ji-yang;ZHANG Peng;NIU Chun-hua;LI Hai-yong;XU Wen-zhu;ZHANG Ying-chen;MA Gang(Department of Urology,Zibo Hospital of Integrated Traditional Chinese and Western Medicine,Zibo,Shandong 255000,China;Department of Urology,the 148 Hospital of PLA,Zibo,Shandong 255300,China;Department of Male Reproductive Medicine&Urology,Center for Reproductive Medicine of Shandong University,Jinan,Shandong 250000,China)

机构地区：[1]淄博市中西医结合医院泌尿外科,山东淄博255000 [2]解放军第一四八医院泌尿外科,山东淄博255300 [3]山东大学附属生殖医院泌尿外科和男性生殖科,山东济南250000

出　　处：《中华男科学杂志》2025年第4期319-322,共4页National Journal of Andrology

摘　　要：目的:探讨慢性前列腺炎(CP)伴精索静脉曲张(VC)患者行精索静脉高位结扎术CP症状及血清睾酮水平的影响。方法:分析2016年1月至2020年12月收治的VC患者90例,其中合并CP患者33例。观察分析腹腔镜精索静脉高位结扎术前后前列腺按摩液(EPS)中白细胞计数、CP症状指数(NIH-CPSI)评分及血清睾酮水平的变化。结果:术后3个月随访观察,单纯VC患者高位结扎术后前列腺按摩液中白细胞、NIH-CPSI评分和血清睾酮水平均无明显变化,CP合并VC患者高位结扎术后3个月EPS中白细胞计数低于术前[(12.39±4.23)×10~9/L vs(21.36±5.05)×10~9/L,P<0.05]、NIH-CPSI评分较术前明显降低[(12.71±6.21)分vs(26.76±8.43)分,P<0.05]、血清睾酮水平较术前增高[(4.34±1.77) ng/ml vs(2.36±1.05) ng/ml,P<0.05]。结论:CP伴VC患者腹腔镜高位结扎精索静脉可有效降低EPS内白细胞水平,有利于血清睾酮水平的恢复,显著改善CP的症状。Objective:To investigate the effect of laparoscopic high ligation of spermatic cord vein in patients with chronic prostatitis and varicocele prostatitis.Methods:A total of 90 varicocele patients were selected from January 2016 to December 2020,including 33 patients with chronic prostatitis.Changes of white blood cell count,National Institutes of Health chronic prostatitis symptom index(NIH-CPSI) score and serum testosterone level in the expressed prostate secretion(EPS) were observed before and after the operation of laparoscopic high ligation of spermatic vein.Results:All patients were followed up three months after the surgery.There was no significant difference in the white blood cell counts in EPS,NIH-CPSI score,and serum testosterone level in patients with varicocele-only who underwent high ligation surgery after the operation.However,the white blood cell count in the EPS of patients with chronic prostatitis was lower than that before 3 months of operation( [12.39±4.23]×10~9/L vs [21.36±5.05]×10~9/L).The NIH-CPSI score was significantly lower than that before operation( [12.71±6.21] vs [26.76±8.43]).And the serum testosterone level was higher than that before operation([4.34±1.77]ng/ml vs [2.36±1.05]ng/ml).Conclusion:Laparoscopic high ligation of the spermatic vein in patients with chronic prostatitis and varicocele could effectively reduce the number of white blood cells in the EPS,boost the level of serum testosterone and improves symptoms of chronic prostatitis.

关 键 词：精索静脉曲张 慢性前列腺炎 腹腔镜 白细胞计数 

分 类 号：R697.33[医药卫生—泌尿科学] R697.24[医药卫生—外科学]