首诊儿童糖尿病患者合并根霉菌感染4例临床特征分析  

Analysis of clinical features of diabetes mellitus complicated with rhizobium infection in 4 children

作　　者：石莉娜 马静[1] 韩琳琳[1] Shi Lina;Ma Jing;Han Linlin(Department of Respiratory Intervention,Children's Hospital Affiliated to Shandong University,Ji'nan 250000,China)

机构地区：[1]山东大学附属儿童医院呼吸介入科,济南250000

出　　处：《中华实用儿科临床杂志》2025年第4期299-302,共4页Chinese Journal of Applied Clinical Pediatrics

摘　　要：对2023年3月至2024年12月山东大学附属儿童医院呼吸介入科收治的4例首诊1型糖尿病合并根霉菌感染患儿的临床诊疗过程进行回顾性分析。患儿均伴有酮症酸中毒。采用两性霉素B、泊沙康唑、艾沙康唑等抗真菌药物治疗,部分患儿行支气管镜介入或肺叶切除术。结果显示,早期诊断、联合抗真菌治疗及必要的手术干预可改善预后,但根霉菌感染病情复杂,病死率较高,需密切监测。The clinical diagnosis and treatment process of 4 children who were newly diagnosed with type 1 diabetes mellitus complicated with rhizobium infection and admitted to the Department of Respiratory Intervention of Children′s Hospital Affiliated to Shandong University from March 2023 to December 2024 were retrospectively analyzed.All pediatric patients presented with ketoacidosis.Treatment included antifungal medications such as Amphotericin B,Posaconazole,and Isavuconazole.Some patients underwent bronchoscopic intervention or lobectomy.The results indicate that early diagnosis,combined antifungal therapy,and necessary surgical intervention can improve prognosis.However,rhziobium is a complex condition with a high mortality rate,requiring close monitoring.

关 键 词：儿童 1型糖尿病 根霉菌 支气管镜 

分 类 号：R725.1[医药卫生—儿科]