2013-2022年济南市戊型病毒性肝炎流行特征分析  

Epidemiological characteristics of hepatitis E in Jinan city from 2013 to 2022

作　　者：贺玉静 徐颖 王琼 孙红云 邹丽萍 HE Yujing;XU Ying;WANG Qiong;SUN Hongyun;ZOU Liping(Jinan Center for Disease Control and Prevention Immunoprophylaxis institute,Jinan,Shandong 250021,China)

机构地区：[1]济南市疾病预防控制中心免疫预防所,山东济南250021

出　　处：《社区医学杂志》2025年第2期49-54,共6页Journal Of Community Medicine

摘　　要：目的 描述性分析济南市戊型病毒性肝炎(戊肝)流行病学特征,为制定本地戊肝防控策略提供科学依据。方法 通过中国疾病预防控制信息系统收集发病日期为2013-01-01-2022-12-31戊肝病例资料,采用描述性流行病学方法分析戊肝时间、地区和人群分布特征,计算年度变化百分比(APC)分析戊肝发病率趋势,应用圆形分布分析方法计算戊肝的季节规律和月分布特点。结果 2013-2022年济南市共报告戊肝813例,各年报告发病率在0.60/10万~1.29/10万;年均报告发病率为0.94/10万。2013-2018年,济南市戊肝发病整体保持平稳趋势(APC=-6.703,P=0.072);2018-2022年呈逐年上升趋势,APC上升了20.02%(P=0.008)。1~4月为发病高峰,占病例总数的44.16%,发病平均角在3月15日。高发区域主要集中在历下区、市中区、历城区、槐荫区、天桥区人口密集的主城区。男女性别比2.58∶1;发病年龄以40岁以上人群为主,60~岁组人群发病率最高(2.63/10万),其次为80~岁组(1.72/10万),0~岁组儿童发病率最低(0.06/10万),年均报告发病率总体上随年龄增长呈升高趋势,χ^(2)=616.086,P<0.001;职业分布前3位的是农民、离退人员、家务及待业。戊肝发病主要以散发为主,偶发食源性聚集性病例。结论 济南市2013-2018年戊肝发病变化趋势不明显,2018-2022年戊肝发病率呈上升趋势。40岁以上人群发病率较高,农民、离退人员、家务及待业人员是重点人群,需加强重点人群健康教育和戊肝疫苗接种工作。Objective To descriptively analyze the epidemiological characteristics of hepatitis E in Jinan city and provide a scientific basis for formulating local prevention and control strategies for hepatitis E.Methods The data of hepatitis E ca-ses with the onset date from January 1,2013 to December 31,2022 were collected through the Chinese Information Sys-tem for Disease Control and Prevention.Descriptive epidemiological methods were used to analyze the temporal,regional and population distribution characteristics of hepatitis E.The annual percentage change(APC)was calculated to analyze the incidence trend of hepatitis E.The circular distribution analysis method was applied to calculate the seasonal and monthly distribution characteristics of hepatitis E.Results From 2013 to 2022,a total of 813 cases of hepatitis E were re-ported in Jinan city.The reported incidence rate in each year ranged from 0.60/100000 to 1.29/100000,with an average annual reported incidence rate of 0.94/100000.From 2013 to 2018,the incidence of hepatitis E in Jinan remained stable overall(APC=-6.703,P=0.072).From 2018 to 2022,it showed an increasing trend year by year,with the APC in-creasing by 20.02%(P=0.008).The peak period of incidence was from January to April,accounting for 44.16%of the total number of cases,and the average incidence angle was on March 15.The high-incidence areas were mainly concen-trated in the densely populated main urban areas such as Lixia district,Shizhong district,Licheng district,Huaiyin dis-trict and Tianqiao district.The male-to-female sex ratio was 2.58:1.The age of onset was mainly among people over 40 years old.The incidence rate was the highest in the 60-age group(2.63/100000),followed by the 80-age group(1.72/100000),and the lowest in children aged 0-age group(0.06/100000).The average annual reported incidence rate generally showed an increasing trend with age(χ^(2)_(trend)=616.086,P<0.001).The top three occupations were farm-ers,retirees,and domestic workers and the unemployed.The incidence of hepatitis E w

关 键 词：戊型病毒性肝炎 流行特征 流行病学调查 聚集性病例 戊肝疫苗 

分 类 号：R512.6[医药卫生—内科学]