帕瑞昔布钠联合罗哌卡因用于痔术后镇痛的疗效观察  

Clinical Efficacy of Parecoxib Sodium Combined with Ropivacaine for Postoperative Analgesia of Hemorrhoids

作　　者：董超科 张春韶 郭晓纯 DONG Chao-ke;ZHANG Chun-shao;GUO Xiao-chun(Department of Coloproctology,Longgang Central Hospital,Shenzhen,Guangdong 518000;Longgang District Orthopedic Hospital,Shenzhen,Guangdong 518000)

机构地区：[1]深圳市龙岗中心医院肛肠科,广东深圳518000 [2]深圳市龙岗区骨科医院,广东深圳518000

出　　处：《中国肛肠病杂志》2025年第3期54-56,共3页Chinese Journal of Coloproctology

基　　金：2021年龙岗区医疗卫生科技计划项目(非扶持类)(编号LGWJ2021-7)。

摘　　要：目的:评估帕瑞昔布钠联合罗哌卡因用于痔术后镇痛的临床效果。方法:选取2022年2月至2023年8月,接受手术治疗的70例痔患者,随机分为观察组和对照组,每组各35例。对照组术后以罗哌卡因镇痛治疗,观察组术后以帕瑞昔布钠联合罗哌卡因镇痛治疗。比较2组术后疼痛、肛缘水肿、临床指标及不良反应。结果:观察组术后6、12、24、48和72 h的疼痛评分均低于对照组(P<0.05),术后72 h肛缘水肿评分低于对照组(P<0.05),首次排尿时间和创口愈合时间均短于对照组(P<0.05),2组不良反应发生率比较,差异无统计学意义(P>0.05)。结论:痔术后采用帕瑞昔布钠联合罗哌卡因镇痛,镇痛效果显著,可以缓解肛缘水肿,改善临床指标,安全性良好,值得临床推广应用。Objective To evaluate the clinical efficacy of parecoxib sodium combined with ropivacaine for postoperative hemorrhoidal analgesia.Methods From February 2022 to August 2023,total 70 patients with hemorrhoids who received surgical treatment were randomly divided into the observation group and the control group,with 35 cases in each group.The control group received postoperative analgesia with ropivacaine,and the observation group was given parecoxib sodium combined with ropivacaine for postoperative analgesia.Postoperative pain,anal edema,clinical indexes and adverse reactions were compared between the two groups.Results The pain scores of the observation group at the 6th,12th,24th 48th and 72th h after surgery were lower than those of the control group(P<0.05).The anal edge edema scores at the 72h after surgery were lower than those of the control group(P<0.05).The first urination time and wound healing time were shorter than those of the control group(P<0.05),and there was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion The use of parecoxib sodium combined with ropivacaine for analgesia after hemorrhoid surgery has a significant analgesic effect,can relieve perianal edema and improve clinical indicators,which is safe and worthy of clinical promotion and application.

关 键 词：痔 帕瑞昔布钠 罗哌卡因 术后镇痛 

分 类 号：R614[医药卫生—麻醉学]