1例扁弯口吸虫人体感染国内首次报道  

The first human case of Clinostomum complanatum infection in China

作　　者：方正明[1] 雷家慧[1] 关飞[1] FANG Zhengming;LEI Jiahui;GUAN Fei(Department of Pathogenic Biology,Tongji Medical College,Huazhong University of Science and Technology,Wuhan,Hubei 430030,China)

机构地区：[1]华中科技大学同济医学院病原生物学系,湖北武汉430030

出　　处：《中国热带医学》2025年第1期124-126,共3页China Tropical Medicine

摘　　要：某患者,女性,32岁,于2024年9月22日在武汉市某餐馆进食未煮熟的草鱼,当晚感觉食道有异物,到医院行食道镜检查未见异常,3 d后感觉咽部有针扎刺痛感。10月8日自检,见咽部悬雍垂旁有1条伸缩蠕动的红褐色虫体吸附,遂就医。医生取虫时发现虫体附着的粘膜处有溃疡。患者经血吸虫、肺吸虫、肝吸虫、囊虫、裂头蚴、包虫、旋毛虫等7种常见人体寄生蠕虫血清学抗体检测结果均为阴性。取出的虫体呈红褐色,长4 mm,宽2 mm。经盐酸卡红染色显示前端有口吸盘,咽部接肠支,二盲支延续到虫体后端,肠支两旁分出许多细小的侧枝。腹吸盘大于口吸盘,位于虫体前1/4处。睾丸一对,纵列于虫体中后部,卵巢位于两睾之间,子宫位于前睾上方。符合扁弯口吸虫(Clinostomum complanatum,Rud.,1819)的形态学特征。经华中科技大学图书馆188个数据库检索至迄今4.6亿余篇全文资源,确认为扁弯口吸虫人体感染病例国内首次报道。A 32-year-old female patient experienced a foreign body sensation in her esophagus on the evening of September 22,2024,after consuming undercooked grass carp at a restaurant in Wuhan.Esophagoscopy conducted at the hospital revealed no abnormalities.Three days later,she had a stabbing pain in the pharynx.On October 8,upon self-examination,she noticed a red brown worm exhibiting stretching and contracting movements attached near the uvula in her pharynx and then went to the hospital.During the removal of the worm,the doctor observed the ulcers on the mucous membrane.Serological antibody tests for seven common human parasitic worms,including Schistosoma japonicum,Paragonimus westermani,Clonorchis sinensis,cysticercus of Taenia solium,sparganum,hydatid cyst,and Trichinella spiralis,were all negative.The isolated worm was reddish brown,measuring 4 mm in length and 2 mm in width.Staining with hydrochloric carmine dye revealed a morphology consistent with Clinostomum complanatum(Rud.,1819),characterized by an oral sucker at the anterior end,a pharynx connecting to intestinal branches,and two intestinal branches extending to the posterior end of the body with small sub-branches.The ventral sucker,larger than the oral sucker,was located at the front 1/4 of the body.A pair of testes were arranged longitudinally in the mid-posterior part,with an ovary located between the two testes and a uterus located above the upper testis.A comprehensive search of 188 databases comprising more than 460 million full-text articles through the library of Huazhong University of Science and Technology confirmed the first reported case of Clinostomum complanatum infection in humans in China.

关 键 词：扁弯口吸虫 草鱼 未煮熟 人体感染 首次报道 

分 类 号：R532.29[医药卫生—内科学]