成人乙型肝炎疫苗快速免疫研究进展  

Advances in rapid immunization strategies for adult hepatitis B vaccination

作　　者：唐晓荣 饶小玲 刘光远 郭世成[2] TANG Xiaorong;RAO Xiaoling;LIU Guangyuan;GUO Shicheng(Guangchang County Center for Disease Control and Prevention,Fuzhou,Jiangri 344900,China;不详)

机构地区：[1]广昌县疾病预防控制中心,江西抚州344900 [2]江西省疾病预防控制中心

出　　处：《中国预防医学杂志》2025年第3期378-384,共7页Chinese Preventive Medicine

摘　　要：目前中国成人乙型肝炎病毒表面抗原流行率较高,虽然成人乙型肝炎疫苗(hepatitis B vaccine,HepB)常规免疫程序接种可获得较高的免疫应答,但其接种针次多、间隔时间长,时间跨度达半年以上,导致接种率低,接种依从性差。成人HepB快速免疫程序研究有利于提高成人疫苗接种率和接种依从性,为成人提供更好的免疫保护。本研究基于国内外相关研究文献,对成人HepB快速免疫程序研究进展进行综述,为完善我国成人HepB快速免疫程序提供参考。The prevalence of hepatitis B virus surface antigen(HBsAg)among adults in China currently maintains a high level.Although the routine immunization procedure of hepatitis B vaccine(HepB)used for adults can achieve a higher immune response,it typically involves multiple doses and extended intervals,often exceeding six months.This results in low vaccination rates and poor adherence to the immunization schedule.Research on rapid immunization protocols for adult HepB is beneficial for improving vaccination uptake and compliance,ultimately providing better immunological protection for adults.This review synthesizes relevant domestic and international studies on rapid immunization strategies for adult HepB,offering insights to refine rapid immunization programs in China.

关 键 词：乙型肝炎疫苗 快速免疫程序 成人 

分 类 号：R512.62[医药卫生—内科学]